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1
Dental Considerations in Children with Glucose-6-phosphate Dehydrogenase Deficiency (Favism): A Review of the Literature and Case Report.葡萄糖-6-磷酸脱氢酶缺乏症（蚕豆病）患儿的牙科考量：文献综述与病例报告
Case Rep Dent. 2015;2015:506459. doi: 10.1155/2015/506459. Epub 2015 Sep 7.
2
Favism, the commonest form of severe hemolytic anemia in Palestinian children, varies in severity with three different variants of G6PD deficiency within the same community.蚕豆病是巴勒斯坦儿童中最常见的严重溶血性贫血形式，在同一社区内，它的严重程度因葡萄糖-6-磷酸脱氢酶（G6PD）缺乏症的三种不同变体而有所不同。
Blood Cells Mol Dis. 2016 Sep;60:58-64. doi: 10.1016/j.bcmd.2016.07.001. Epub 2016 Jul 6.
3
[Glucose-6-phosphate dehydrogenase deficiency in children: a case report].[儿童葡萄糖-6-磷酸脱氢酶缺乏症：一例报告]
Rev Chil Pediatr. 2014 Feb;85(1):74-9. doi: 10.4067/S0370-41062014000100010.
4
Favism: A Case Report.蚕豆病：一例病例报告。
Cureus. 2022 Mar 17;14(3):e23269. doi: 10.7759/cureus.23269. eCollection 2022 Mar.
5
[Acute hemolytic anemia caused by glucose-6-phosphate dehydrogenase deficiency].葡萄糖-6-磷酸脱氢酶缺乏所致急性溶血性贫血
Ugeskr Laeger. 1999 Aug 30;161(35):4882-3.
6
[Favism].[蚕豆病]
Acta Med Port. 2000 Jul-Aug;13(4):237-40.
7
Glucose-6-phosphate dehydrogenase variants associated with favism in Thai children.与泰国儿童蚕豆病相关的葡萄糖-6-磷酸脱氢酶变体
Int J Hematol. 2006 Feb;83(2):139-43. doi: 10.1532/IJH97.A20513.
8
[Favism after ingestion of fava beans in a three-year-old child with glucose-6-phosphate dehydrogenase deficiency].[一名患有葡萄糖-6-磷酸脱氢酶缺乏症的三岁儿童摄入蚕豆后发生蚕豆病]
Ugeskr Laeger. 2017 May 15;179(20).
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Review and drug therapy implications of glucose-6-phosphate dehydrogenase deficiency.葡萄糖-6-磷酸脱氢酶缺乏症的综述及药物治疗意义
Am J Health Syst Pharm. 2018 Feb 1;75(3):97-104. doi: 10.2146/ajhp160961. Epub 2018 Jan 5.
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Hepatic transcriptional profiling response to fava bean-induced oxidative stress in glucose-6-phosphate dehydrogenase-deficient mice.葡萄糖-6-磷酸脱氢酶缺陷小鼠中肝脏转录谱对蚕豆诱导的氧化应激的反应
Gene. 2018 Apr 30;652:66-77. doi: 10.1016/j.gene.2018.02.014. Epub 2018 Feb 8.

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1
Glucose-6-phosphate dehydrogenase enzyme deficiency as a diagnostic factor of diabetes mellitus: An original study.葡萄糖-6-磷酸脱氢酶缺乏作为糖尿病的诊断因素：一项原创研究。
J Oral Maxillofac Pathol. 2024 Jan-Mar;28(1):96-99. doi: 10.4103/jomfp.jomfp_295_23. Epub 2024 Apr 15.
2
Dental Management of a Patient with Pulmonary Atresia and Ventricular Septal Defect.肺动脉闭锁合并室间隔缺损患者的牙科管理
Front Dent. 2021 Jun 29;18:21. doi: 10.18502/fid.v18i21.6931. eCollection 2021.

本文引用的文献

1
G6PD deficiency in Latin America: systematic review on prevalence and variants.拉丁美洲的葡萄糖-6-磷酸脱氢酶缺乏症：患病率及变异的系统评价
Mem Inst Oswaldo Cruz. 2014 Aug;109(5):553-68. doi: 10.1590/0074-0276140123. Epub 2014 Aug 19.
2
[Glucose-6-phosphate dehydrogenase deficiency in children: a case report].[儿童葡萄糖-6-磷酸脱氢酶缺乏症：一例报告]
Rev Chil Pediatr. 2014 Feb;85(1):74-9. doi: 10.4067/S0370-41062014000100010.
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Medications and glucose-6-phosphate dehydrogenase deficiency: an evidence-based review.药物与葡萄糖-6-磷酸脱氢酶缺乏：循证综述。
Drug Saf. 2010 Sep 1;33(9):713-26. doi: 10.2165/11536520-000000000-00000.
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General medicine and surgery for dental practitioners. Part 2--metabolic disorders.口腔医师实用内科学与外科学。第 2 部分——代谢紊乱。
Br Dent J. 2010 May 8;208(9):389-92. doi: 10.1038/sj.bdj.2010.397.
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Perioperative management of the glucose-6-phosphate dehydrogenase deficient patient: a review of literature.葡萄糖-6-磷酸脱氢酶缺乏症患者的围手术期管理：文献综述
Anesth Prog. 2009 Autumn;56(3):86-91. doi: 10.2344/0003-3006-56.3.86.
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Glucose-6-phosphate dehydrogenase deficiency.葡萄糖-6-磷酸脱氢酶缺乏症
Lancet. 2008 Jan 5;371(9606):64-74. doi: 10.1016/S0140-6736(08)60073-2.
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Apert syndrome with glucose-6-phosphate dehydrogenase deficiency: a case report.伴有葡萄糖-6-磷酸脱氢酶缺乏症的阿佩尔综合征：一例报告
Int J Paediatr Dent. 2006 May;16(3):218-21. doi: 10.1111/j.1365-263X.2006.00696.x.
8
Diagnosis and management of G6PD deficiency.葡萄糖-6-磷酸脱氢酶缺乏症的诊断与管理
Am Fam Physician. 2005 Oct 1;72(7):1277-82.
9
Enzymatic deficiency in primaquine-sensitive erythrocytes.伯氨喹敏感红细胞中的酶缺乏。
Science. 1956 Sep 14;124(3220):484-5. doi: 10.1126/science.124.3220.484-a.
10
Glucose-6-phosphate dehydrogenase deficiency.葡萄糖-6-磷酸脱氢酶缺乏症
Baillieres Best Pract Res Clin Haematol. 2000 Mar;13(1):21-38. doi: 10.1053/beha.1999.0055.

葡萄糖-6-磷酸脱氢酶缺乏症（蚕豆病）患儿的牙科考量：文献综述与病例报告

Dental Considerations in Children with Glucose-6-phosphate Dehydrogenase Deficiency (Favism): A Review of the Literature and Case Report.

作者信息

Hernández-Pérez Daniela, Butrón-Téllez Girón Claudia, Ruiz-Rodríguez Socorro, Garrocho-Rangel Arturo, Pozos-Guillén Amaury

机构信息

Pediatric Dentistry Postgraduate Program, Faculty of Dentistry, San Luis Potosi University, 2 Dr. Manuel Nava, Zona Universitaria, 78290 San Luis Potosí, SLP, Mexico.

出版信息

Case Rep Dent. 2015;2015:506459. doi: 10.1155/2015/506459. Epub 2015 Sep 7.

DOI:10.1155/2015/506459
PMID:26435857
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4575995/
Abstract

Glucose-6-phosphate dehydrogenase (G6PD) deficiency is an uncommon inherited enzyme deficiency characterized by hemolytic anemia, caused by the inability of erythrocytes to detoxify oxidizing agents such as drugs, infectious diseases, or fava bean ingestion. In this later case, the disorder is known as favism. The aim of the present report was to present a review of the literature in this disease, to describe a case report concerning an affected 9-year-old male, and to review the main implications and precautions in pediatric dental management.

摘要

葡萄糖-6-磷酸脱氢酶（G6PD）缺乏症是一种罕见的遗传性酶缺乏症，其特征为溶血性贫血，这是由于红细胞无法对药物、传染病或食用蚕豆等氧化剂进行解毒所致。在后一种情况下，该病症被称为蚕豆病。本报告的目的是对该疾病的文献进行综述，描述一例9岁患病男性的病例报告，并探讨儿科牙科管理中的主要影响因素和注意事项。