Sainsbury Laboratory (SLCU), University of Cambridge, Cambridge CB2 1LR, United Kingdom; email:
Annu Rev Cell Dev Biol. 2015;31:201-29. doi: 10.1146/annurev-cellbio-102314-112502. Epub 2015 Sep 30.
Plant-pathogen interactions can result in dramatic visual changes in the host, such as galls, phyllody, pseudoflowers, and altered root-system architecture, indicating that the invading microbe has perturbed normal plant growth and development. These effects occur on a cellular level but range up to the organ scale, and they commonly involve attenuation of hormone homeostasis and deployment of effector proteins with varying activities to modify host cell processes. This review focuses on the cellular-reprogramming mechanisms of filamentous and bacterial plant pathogens that exhibit a biotrophic lifestyle for part, if not all, of their lifecycle in association with the host. We also highlight strategies for exploiting our growing knowledge of microbial host reprogramming to study plant processes other than immunity and to explore alternative strategies for durable plant resistance.
植物-病原体相互作用可导致宿主发生明显的视觉变化，如瘤、叶增生、假花和改变的根系结构，表明入侵微生物扰乱了正常的植物生长和发育。这些影响发生在细胞水平上，但范围可达到器官尺度，它们通常涉及激素动态平衡的衰减和效应蛋白的部署，这些蛋白具有不同的活性，可改变宿主细胞的过程。本综述重点介绍了表现出生物营养生活方式的丝状和细菌植物病原体的细胞重编程机制，它们在与宿主的部分（如果不是全部）生命周期中表现出这种生活方式。我们还强调了利用我们对微生物宿主重编程的不断增长的知识来研究除免疫以外的植物过程以及探索持久植物抗性的替代策略的策略。
