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麻醉深度对斜视手术中眼心反射的影响。

The effect of anesthesia depth on the oculocardiac reflex in strabismus surgery.

作者信息

Karaman Tugba, Demir Selim, Dogru Serkan, Şahin Aynur, Tapar Hakan, Karaman Serkan, Kaya Ziya, Suren Mustafa, Arici Semih

机构信息

Department of Anesthesiology and Reanimation, Gaziosmanpasa University School of Medicine, 60100, Tokat, Turkey.

Department of Ophthalmology, Gaziosmanpasa University School of Medicine, Tokat, Turkey.

出版信息

J Clin Monit Comput. 2016 Dec;30(6):889-893. doi: 10.1007/s10877-015-9789-1. Epub 2015 Oct 5.

Abstract

The aim of this study was to investigate the effect of the bispectral index (BIS) guided depth of anesthesia to inhibition of the oculocardiac reflex (OCR) during pediatric strabismus surgery. Patients between the ages of 3 and 16 years who were scheduled for elective strabismus surgery were randomly assigned to two groups. In Group 1 (n: 32), the BIS values of the patients were maintained at <50; in Group 2 (n: 28), the BIS values of the patients were maintained at levels greater than or equal to 50 with 4-7 % desflurane in a 50 % O-air mixture by titrating the concentration during the surgery. The heart rates, presence of dysrhythmia, anticholinergic drug usage and the type of the operated extra ocular muscle were recorded. The incidence of OCR was 25 % in Groups 1 and 64.3 % in Group 2, (p < 0.05). Moreover, the incidence of OCR in group 2 was higher in medial rectus (MR) traction (78.9 %) than in lateral rectus (LR) traction (33.3 %) (p = 0.035), with no significant difference in Group 1 between MR (21.1 %) and LR (26.7 %) tractions (p = 0.83). We found that the lower BIS values are associated with the lower incidence of OCR in pediatric patients undergoing strabismus surgery. And our findings confirmed that the deeper anesthesia has a protective effect against the OCR.

摘要

本研究旨在探讨在小儿斜视手术中,脑电双频指数(BIS)引导的麻醉深度对眼心反射(OCR)抑制的影响。将计划接受择期斜视手术的3至16岁患者随机分为两组。第1组(n = 32),患者的BIS值维持在<50;第2组(n = 28),在手术过程中通过滴定浓度,使用50%氧气-空气混合气体中的4%-7%地氟醚,将患者的BIS值维持在大于或等于50的水平。记录心率、心律失常情况、抗胆碱能药物使用情况以及手术的眼外肌类型。第1组OCR发生率为25%,第2组为64.3%,(p < 0.05)。此外,第2组在内直肌(MR)牵引时OCR发生率(78.9%)高于外直肌(LR)牵引时(33.3%)(p = 0.035),而第1组MR(21.1%)和LR(26.7%)牵引时无显著差异(p = 0.83)。我们发现,在接受斜视手术的小儿患者中,较低的BIS值与较低的OCR发生率相关。我们的研究结果证实,较深的麻醉对OCR有保护作用。

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