Shi Chuan, Kang Lan, Yao Shuqiao, Ma Yibin, Li Tao, Liang Ying, Cheng Zhang, Xu Yifeng, Shi Jianguo, Xu Xiufeng, Zhang Congpei, Franklin Donald R, Heaton Robert K, Jin Hua, Yu Xin
Peking University Institute of Mental Health (Sixth Hospital), Beijing, China; National Clinical Research Center for Mental Disorders (Peking University Sixth Hospital) Beijing, China; Key Laboratory of Mental Health, Ministry of Health (Peking University), Beijing, China.
The Medical Psychological Research Center, Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Schizophr Res. 2015 Dec;169(1-3):109-115. doi: 10.1016/j.schres.2015.09.003. Epub 2015 Oct 4.
MATRICS Consensus Cognitive Battery (MCCB), packaging 10 tests selected from more than 90 nominated tests, is a method developed by the Measurement and Treatment Research to Improve Cognition in Schizophrenia (MATRICS) group to evaluate the efficacy of treatments targeting cognitive impairments in schizophrenia. MCCB had been translated into a number of languages, but only the US and Spain had normative data reported. Inconsistency in translation and cultural differences make direct application of MCCB in China problematic. In this study, we administered the battery to a representative community sample based on Chinese population census in 2005 and obtained normative data. The effects of age, gender, education level, and scale of residence area on test performance were examined. The sample included 656 healthy volunteers from six sites in China. At each site, sample was stratified according to age, gender, and educational level, and scale of the area one was born in, grew up in and currently living in was recorded. We found age, gender, and education had significant effects on the normative data for MCCB in China, which are comparable to those found for the original standardized English version in the U.S. and the Spanish version in Spain. Remarkably, the residence scale effects on neuropsychological performance were significant, which should be taking into account when calculating the standardized T score for each subject. The practice effects were minor and test-retest reliability of MCCB was good, which suggests MCCB as an appropriate measure for clinical and research usage in China.
精神分裂症认知功能成套测验共识版(MATRICS Consensus Cognitive Battery,MCCB)从90多项提名测验中选取了10项测验,是由改善精神分裂症认知功能测量与治疗研究(MATRICS)小组开发的一种评估针对精神分裂症认知障碍治疗效果的方法。MCCB已被翻译成多种语言,但只有美国和西班牙报告了常模数据。翻译的不一致和文化差异使得MCCB在中国直接应用存在问题。在本研究中,我们基于2005年中国人口普查对一个具有代表性的社区样本进行了该成套测验,并获得了常模数据。研究了年龄、性别、教育水平和居住地区规模对测验成绩的影响。样本包括来自中国六个地点的656名健康志愿者。在每个地点,样本根据年龄、性别和教育水平进行分层,并记录其出生、成长和当前居住地区的规模。我们发现年龄、性别和教育对中国MCCB的常模数据有显著影响,这与在美国发现的原始标准化英语版本和西班牙的西班牙语版本相当。值得注意的是,居住规模对神经心理表现的影响显著,在计算每个受试者的标准化T分数时应予以考虑。练习效应较小,MCCB的重测信度良好,这表明MCCB适合在中国用于临床和研究。