Department of Psychiatry, Instituto de Investigación Hospital 12 de Octubre, Madrid, Spain.
Schizophr Res. 2012 Feb;134(2-3):279-84. doi: 10.1016/j.schres.2011.11.026. Epub 2011 Dec 20.
The MATRICS Consensus Cognitive Battery (MCCB), developed by the National Institute of Mental Health (NIMH) Measurement and Treatment Research to Improve Cognition in Schizophrenia (MATRICS) initiative, has been recommended as the standard battery for clinical trials of cognition-enhancing interventions for schizophrenia. Normative data for the MCCB has been previously obtained in the U.S. Extrapolation of these normative data to different countries may be problematic due to the translation of the different tests, as well as potential cultural influences. We present the process of obtaining normative data for the MCCB in Spain with administration of the battery to a general community standardization sample. In addition, we examine the influence of age, gender, and educational level on test performance. The MCCB was administered to a total sample of 210 healthy volunteers, at three Spanish sites. For each site, recruitment of the sample was stratified according to age, gender, and educational level. Our findings indicate significant age, gender, and education effects on the normative data for the MCCB in Spain, which are comparable to those effects described for the original standardized English version in the U.S. The fact that the normative data are comparable, and that the variables age, gender, and education have a similar influence on performance, supports the robustness of the MCCB for use in different countries.
由美国国家心理健康研究所(NIMH)的“测量和治疗研究以改善精神分裂症认知(MATRICS)”计划开发的 MATRICS 共识认知电池(MCCB)已被推荐为精神分裂症认知增强干预临床试验的标准电池。MCCB 的常模数据以前在美国获得过。由于不同测试的翻译以及潜在的文化影响,将这些常模数据推断到不同的国家可能会出现问题。我们展示了在西班牙获得 MCCB 常模数据的过程,方法是对一般社区标准化样本进行电池测试。此外,我们还研究了年龄、性别和教育水平对测试表现的影响。MCCB 共对三个西班牙地点的 210 名健康志愿者进行了测试。对于每个地点,根据年龄、性别和教育水平对样本进行分层招募。我们的研究结果表明,西班牙 MCCB 的常模数据存在显著的年龄、性别和教育影响,这些影响与美国原始标准化英语版本描述的影响相当。常模数据具有可比性,并且年龄、性别和教育等变量对表现的影响相似,这支持了 MCCB 在不同国家使用的稳健性。