Simbauranga Rehema H, Kamugisha Erasmus, Hokororo Adolfine, Kidenya Benson R, Makani Julie
Department of Paediatrics and Child health, Catholic University of Health and Allied Sciences, Box 1464, Mwanza, Tanzania.
Department of Biochemistry and Molecular Biology, Catholic University of Health and Allied Sciences, Box 1464, Mwanza, Tanzania.
BMC Hematol. 2015 Oct 12;15:13. doi: 10.1186/s12878-015-0033-5. eCollection 2015.
Anaemia is a major public health problem in developing countries, contributing significantly to morbidity and mortality amongst children under-five years of age. About 43 % of under-fives are anaemic worldwide, and two-thirds reside in sub-Saharan Africa. Even where blood transfusion is available for treatment there is still a significant case fatality rate ranging between 6 and 18 %. This study aimed to determine the prevalence and morphological types of anaemia, as well as factors associated with severe anaemia in under-five children admitted at Bugando Medical Centre (BMC).
This was a hospital-based, cross-sectional study conducted between November 2012 and February 2013. Selected laboratory investigations were done on children admitted to BMC. Anaemia was defined using WHO criteria.
A total of 448 under-five children were recruited into the study. The overall prevalence of anaemia was 77.2 % (346/448) with mild, moderate and severe anaemia being 16.5, 33 and 27.7 % respectively. Microcytic hypochromic anaemia was detected in 37.5 % of the children with anaemia. Of 239 children with moderate and severe anaemia, 22.6 % (54/239) had iron deficiency anaemia based on serum ferritin level less than12 μg/ml. The factors associated with severe anaemia included unemployment of the parent, malaria parasitaemia and presence of sickle haemoglobin.
The prevalence of anaemia among under-five children admitted at BMC was high. Iron deficiency anaemia was the most common type. Factors associated with severe anaemia were unemployment among caretakers, malaria parasitaemia and presence of sickle haemoglobin.
贫血是发展中国家的一个主要公共卫生问题,对五岁以下儿童的发病率和死亡率有重大影响。全球约43%的五岁以下儿童患有贫血,其中三分之二居住在撒哈拉以南非洲。即使在有输血治疗的地方,仍有6%至18%的显著病死率。本研究旨在确定布甘多医疗中心(BMC)收治的五岁以下儿童贫血的患病率和形态学类型,以及与严重贫血相关的因素。
这是一项于2012年11月至2013年2月进行的基于医院的横断面研究。对入住BMC的儿童进行了选定的实验室检查。贫血采用世界卫生组织标准定义。
共有448名五岁以下儿童纳入本研究。贫血的总体患病率为77.2%(346/448),轻度、中度和重度贫血分别为16.5%、33%和27.7%。37.5%的贫血儿童检测出小细胞低色素性贫血。在239名中度和重度贫血儿童中,22.6%(54/239)根据血清铁蛋白水平低于12μg/ml诊断为缺铁性贫血。与严重贫血相关的因素包括父母失业、疟疾寄生虫血症和镰状血红蛋白的存在。
BMC收治的五岁以下儿童贫血患病率较高。缺铁性贫血是最常见的类型。与严重贫血相关的因素是照顾者失业、疟疾寄生虫血症和镰状血红蛋白的存在。