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富血小板血浆在使用腘绳肌进行前交叉韧带重建手术中预防股骨隧道扩大的潜在积极作用:一项针对51例患者的临床研究

The Potentially Positive Role of PRPs in Preventing Femoral Tunnel Widening in ACL Reconstruction Surgery Using Hamstrings: A Clinical Study in 51 Patients.

作者信息

Starantzis Konstantinos A, Mastrokalos Dimitrios, Koulalis Dimitrios, Papakonstantinou Olympia, Soucacos Panayiotis N, Papagelopoulos Panayiotis J

机构信息

1st Department of Orthopaedics, ATTIKON University General Hospital, University of Athens, 124 62 Athens, Greece.

出版信息

J Sports Med (Hindawi Publ Corp). 2014;2014:789317. doi: 10.1155/2014/789317. Epub 2014 Nov 6.

DOI:10.1155/2014/789317
PMID:26464895
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4590903/
Abstract

Purpose. In this study, the early and midterm clinical and radiological results of the anterior cruciate ligament (ACL) reconstruction surgery with or without the use of platelet rich plasma (PRP) focusing on the tunnel-widening phenomenon are evaluated. Methods. This is a double blind, prospective randomized study. 51 patients have completed the assigned protocol. Recruited individuals were divided into two groups: a group with and a group without the use of PRPs. Patients were assessed on the basis of MRI scans, which were performed early postoperatively and repeated at least one-year postoperatively. The diameter was measured at the entrance, at the bottom, and at the mid distance of the femoral tunnel. Results. Our study confirmed the existence of tunnel widening as a phenomenon. The morphology of the dilated tunnels was conical in both groups. There was a statistical significant difference in the mid distance of the tunnels between the two groups. This finding may support the role of a biologic response secondary to mechanical triggers. Conclusions. The use of RPRs in ACL reconstruction surgery remains a safe option that could potentially eliminate the biologic triggers of tunnel enlargement. The role of mechanical factors, however, remains important.

摘要

目的。在本研究中,评估了使用或不使用富血小板血浆(PRP)进行前交叉韧带(ACL)重建手术的早期和中期临床及放射学结果,重点关注隧道扩大现象。方法。这是一项双盲、前瞻性随机研究。51名患者完成了指定方案。招募的个体被分为两组:一组使用PRP,一组不使用PRP。根据术后早期及术后至少一年重复进行的MRI扫描对患者进行评估。在股骨隧道的入口、底部和中间距离处测量直径。结果。我们的研究证实了隧道扩大现象的存在。两组中扩张隧道的形态均为圆锥形。两组之间隧道的中间距离存在统计学显著差异。这一发现可能支持机械触发引发生物反应的作用。结论。在ACL重建手术中使用RPR仍然是一种安全的选择,有可能消除隧道扩大的生物触发因素。然而,机械因素的作用仍然很重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2210/4590903/e29d2db88319/JSM2014-789317.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2210/4590903/dda85defcd0f/JSM2014-789317.001.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2210/4590903/cb7435815e20/JSM2014-789317.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2210/4590903/f8dd59d9f747/JSM2014-789317.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2210/4590903/e29d2db88319/JSM2014-789317.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2210/4590903/dda85defcd0f/JSM2014-789317.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2210/4590903/d3a0e0c9abbc/JSM2014-789317.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2210/4590903/cb7435815e20/JSM2014-789317.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2210/4590903/f8dd59d9f747/JSM2014-789317.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2210/4590903/e29d2db88319/JSM2014-789317.005.jpg

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Arthroscopy. 2010 Jan;26(1):50-7. doi: 10.1016/j.arthro.2009.06.030.
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Femoral tunnel enlargement after anatomic ACL reconstruction: a biological problem?解剖学 ACL 重建后股骨隧道扩大:生物学问题?
Knee Surg Sports Traumatol Arthrosc. 2010 Sep;18(9):1189-94. doi: 10.1007/s00167-010-1046-z. Epub 2010 Jan 29.
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Has platelet-rich plasma any role in anterior cruciate ligament allograft healing?
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