Scammell A M, Diver M J
Institute of Child Health, University of Liverpool.
Arch Dis Child. 1989 Jan;64(1):139-41. doi: 10.1136/adc.64.1.139.
Eight infants had paired measurements of plasma aldosterone and plasma renin activity while being treated for congestive heart failure. There is parallelism with aldosterone and renin activity in the presence of a hyperactive renin-angiotensin-aldosterone system. Six patients had plasma renin activity and plasma aldosterone measured after commencing captopril and we have shown biochemical blockade of the renin-angiotensin-aldosterone system.
八名婴儿在接受充血性心力衰竭治疗期间进行了血浆醛固酮和血浆肾素活性的配对测量。在肾素 - 血管紧张素 - 醛固酮系统亢进的情况下，醛固酮和肾素活性呈平行关系。六名患者在开始使用卡托普利后测量了血浆肾素活性和血浆醛固酮，我们已证实肾素 - 血管紧张素 - 醛固酮系统的生化阻断作用。
