Zhou Deqing, Su Laijin, Zhao Feng, Ma Liping
Bing Du Xue Bao. 2015 May;31(3):313-7.
Noroviruses (NoVs) are one of the most important foodborne viral pathogens worldwide. Shellfish are the most common carriers of NoVs as they can concentrate and accumulate large amounts of the virus through filter feeding from seawater. Shellfish may selectively accumulate NoVs with different genotypes, and this bioaccumulation may depend on the season and location. Our previous studies found various histo-blood group antigens (HBGAs) in shellfish tissues. While HBGAs might be the main reason that NoVs are accumulated in shellfish, the detailed mechanism behind NoV concentration and bioaccumulation in shellfish is not clear. Here we review current research into NoV bioaccumulation, tissue distribution, seasonal variation, and binding mechanism in shellfish. This paper may provide insight into controlling NoV transmission and decreasing the risks associated with shellfish consumption.
诺如病毒（NoVs）是全球最重要的食源性病毒病原体之一。贝类是诺如病毒最常见的载体，因为它们可以通过从海水中滤食来浓缩和积累大量病毒。贝类可能会选择性地积累不同基因型的诺如病毒，这种生物积累可能取决于季节和地点。我们之前的研究在贝类组织中发现了多种组织血型抗原（HBGAs）。虽然HBGAs可能是诺如病毒在贝类中积累的主要原因，但诺如病毒在贝类中浓缩和生物积累背后的详细机制尚不清楚。在此，我们综述了目前关于诺如病毒在贝类中的生物积累、组织分布、季节变化和结合机制的研究。本文可能为控制诺如病毒传播和降低与食用贝类相关的风险提供见解。
