Mittal N, Vatsa S, Minz Aka
Department of Laboratory Medicine, QRG Central Hospital and Research Centre, Faridabad, Haryana, India.
Indian J Med Microbiol. 2015 Oct-Dec;33(4):590-3. doi: 10.4103/0255-0857.167337.
Cryptococcal meningitis in immunocompetent post-partum women has been rarely reported. Immune restoration during post-partum period leads to unmasking of many opportunistic infections that may have been acquired during pregnancy but manifest itself in the post-partum period due to immune reconstitution inflammatory syndrome. This case highlights the importance of considering opportunistic pathogens in immunocompetent patients who may be undergoing immune restoration. We report here a fatal case of post-partum immunocompetent women who presented with clinical features of meningitis. Prognosis of the cryptococcal meningitis not only depends on the immune status of the patient but also on how early the disease is diagnosed in the course of illness.
免疫功能正常的产后女性患隐球菌性脑膜炎的病例鲜有报道。产后免疫恢复会使许多可能在孕期感染但因免疫重建炎症综合征而在产后显现的机会性感染被揭示出来。该病例凸显了在可能正在经历免疫恢复的免疫功能正常患者中考虑机会性病原体的重要性。我们在此报告一例产后免疫功能正常女性的致命病例，该患者表现出脑膜炎的临床特征。隐球菌性脑膜炎的预后不仅取决于患者的免疫状态，还取决于疾病在病程中被诊断的早晚。
