Wong Michael, Woody Erik Z, Schmidt Louis A, Ameringen Michael Van, Soreni Noam, Szechtman Henry
Department of Psychiatry and Behavioural Neurosciences, McMaster University , Hamilton, ON, Canada.
Department of Psychology, University of Waterloo , Waterloo, ON, Canada.
Front Psychol. 2015 Sep 29;6:1480. doi: 10.3389/fpsyg.2015.01480. eCollection 2015.
Previous studies have shown that the resting electroencephalogram (EEG) alpha patterns of non-clinical participants who score high on measures of negative affect, such as depression and shyness, are different from those who score low. However, we know relatively little about patterns of resting EEG alpha patterns in a non-clinical sample of individuals with high levels of obsessive-compulsive behaviors indicative of obsessive-compulsive disorder (OCD). Here we measured resting EEG alpha activity in frontal and parietal regions of non-clinical participants who scored high and low on the Padua-R, a measure of the severity of OCD-related behaviors. We found that participants who scored high on the Padua-R exhibited decreased overall activity in frontal regions relative to individuals who scored low on the measure. We speculate that frontal hypoactivity may be a possible marker and/or index of risk for OCD.
先前的研究表明，在诸如抑郁和害羞等消极情绪测量中得分较高的非临床参与者的静息脑电图（EEG）阿尔法模式，与得分较低的参与者不同。然而，对于具有表明强迫症（OCD）的高水平强迫行为的非临床个体样本中的静息EEG阿尔法模式，我们了解得相对较少。在此，我们测量了在帕多瓦量表（Padua-R，一种测量与OCD相关行为严重程度的量表）上得分高低的非临床参与者额叶和顶叶区域的静息EEG阿尔法活动。我们发现，在帕多瓦量表上得分高的参与者相对于得分低的个体，额叶区域的整体活动有所下降。我们推测额叶活动减退可能是OCD风险的一个可能标志和/或指标。
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