Zogg Cheryl K, Najjar Peter, Diaz Arturo J Rios, Zogg Donald L, Tsai Thomas C, Rose John A, Scott John W, Gani Faiz, Alshaikh Husain, Canner Joseph K, Schneider Eric B, Goldberg Joel E, Haider Adil H
*Center for Surgery and Public Health: Harvard Medical School, Harvard T.H. Chan School of Public Health, and Department of Surgery, Brigham and Women's Hospital, Boston, MA†Minnesota Gastroenterology, P.A., Saint Paul, MN‡Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD.
Ann Surg. 2016 Aug;264(2):312-22. doi: 10.1097/SLA.0000000000001511.
To compare incremental costs associated with complications of elective colectomy using nationally representative data among patients undergoing laparoscopic/open resections for the 4 most frequent diagnoses.
Rising healthcare costs have led to increasing focus on the need to achieve a better understanding of the association between costs and quality. Among elective colectomies, a focus of surgical quality-improvement initiatives, interpretable evidence to support existing approaches is lacking.
The 2009 to 2011 Nationwide Inpatient Sample (NIS) data were queried for adult (≥18 years) patients undergoing elective colectomy. Patients with primary diagnoses for colon cancer, diverticular disease, benign colonic neoplasm, and ulcerative colitis/regional enteritis were included. Based on system-based complications considered relevant to long-term treatment of elective colectomy, stratified differences in risk-adjusted incremental hospital costs and complications probabilities were compared.
A total of 68,462 patients were included, weighted to represent 337,887 patients nationwide. A total of 16.4% experienced complications. Annual risk-adjusted incremental costs amounted to >$150 million. Magnitudes of complication prevalences/costs varied by primary diagnosis, operative technique, and complication group. Infectious complications contributed the most ($55 million), followed by gastrointestinal ($53 million), pulmonary ($22 million), and cardiovascular ($11 million) complications. Total annual costs for elective colectomies amounted to >$1.7 billion: 11.3% was due to complications [1.9% due to current Centers for Medicare and Medicaid Services (CMS) complications].
The results highlight a need to consider the varied/broad impact of complications, offering a stratified paradigm for priority setting in surgery. As we move forward in the development of novel/adaptation of existing interventions, it will be essential to weigh the cost of complications in an evidence-based way.
利用全国代表性数据,比较因4种最常见诊断接受腹腔镜/开放切除术的患者行择期结肠切除术后并发症的增量成本。
不断上涨的医疗成本促使人们越来越关注更好地理解成本与质量之间关联的必要性。在择期结肠切除术中,作为手术质量改进举措的重点,缺乏支持现有方法的可解释证据。
查询2009年至2011年全国住院患者样本(NIS)数据,以获取接受择期结肠切除术的成年(≥18岁)患者。纳入原发性诊断为结肠癌、憩室病、良性结肠肿瘤以及溃疡性结肠炎/局限性肠炎的患者。基于与择期结肠切除术长期治疗相关的系统性并发症,比较风险调整后的增量住院成本和并发症概率的分层差异。
共纳入68462例患者,加权后代表全国337887例患者。共有16.4%的患者出现并发症。年度风险调整后的增量成本超过1.5亿美元。并发症患病率/成本的幅度因原发性诊断、手术技术和并发症组而异。感染性并发症贡献最大(5500万美元),其次是胃肠道并发症(5300万美元)、肺部并发症(2200万美元)和心血管并发症(1100万美元)。择期结肠切除术的年度总成本超过17亿美元:11.3%归因于并发症[1.9%归因于当前医疗保险和医疗补助服务中心(CMS)认定的并发症]。
结果凸显了考虑并发症多样/广泛影响的必要性,为手术中的优先事项设定提供了分层范例。在我们推进新型干预措施的开发/对现有干预措施进行调整时,以循证方式权衡并发症成本至关重要。