Deminice R, Rosa F T, Pfrimer K, Ferrioli E, Jordao A A, Freitas E
Department of Physical Education, State University of Londrina, Londrina, Brazil.
Faculty of Medicine of Ribeirao Preto, University of Sao Paulo, Ribeirao Preto, Brazil.
Int J Sports Med. 2016 Feb;37(2):149-53. doi: 10.1055/s-0035-1559690. Epub 2015 Oct 28.
This study aimed to evaluate changes in total body water (TBW) in soccer athletes using a deuterium oxide dilution method and bioelectrical impedance (BIA) formulas after 7 days of creatine supplementation. In a double-blind controlled manner, 13 healthy (under-20) soccer players were divided randomly in 2 supplementation groups: Placebo (Pla, n=6) and creatine supplementation (CR, n=7). Before and after the supplementation period (0.3 g/kg/d during 7 days), TBW was determined by deuterium oxide dilution and BIA methods. 7 days of creatine supplementation lead to a large increase in TBW (2.3±1.0 L) determined by deuterium oxide dilution, and a small but significant increase in total body weight (1.0±0.4 kg) in Cr group compared to Pla. The Pla group did not experience any significant changes in TBW or body weight. Although 5 of 6 BIA equations were sensitive to determine TBW changes induced by creatine supplementation, the Kushner et al. 16 method presented the best concordance levels when compared to deuterium dilution method. In conclusion, 7-days of creatine supplementation increased TBW determined by deuterium oxide dilution or BIA formulas. BIA can be useful to determine TBW changes promoted by creatine supplementation in soccer athletes, with special concern for formula choice.
本研究旨在评估使用重水稀释法和生物电阻抗（BIA）公式，在补充肌酸7天后足球运动员全身水（TBW）的变化。以双盲对照方式，将13名健康的（20岁以下）足球运动员随机分为2个补充组：安慰剂组（Pla，n = 6）和肌酸补充组（CR，n = 7）。在补充期前后（7天内每天0.3 g/kg），通过重水稀释法和BIA方法测定TBW。与安慰剂组相比，肌酸补充组补充7天后，通过重水稀释法测定的TBW大幅增加（2.3±1.0 L），总体重小幅但显著增加（1.0±0.4 kg）。安慰剂组的TBW和体重没有任何显著变化。虽然6个BIA公式中有5个对测定肌酸补充引起的TBW变化敏感，但与重水稀释法相比，Kushner等人的16法呈现出最佳的一致性水平。总之，补充7天肌酸可增加通过重水稀释法或BIA公式测定的TBW。BIA可用于测定足球运动员中肌酸补充引起的TBW变化，特别要关注公式的选择。
