Samanta Moumita, Mondal Rakesh, Shah Ankit, Hazra Avijit, Ray Somosri, Dhar Goutam, Biswas Rupa, Sabui Tapas Kumar, Raychaudhuri Dibyendu, Chatterjee Kaushani, Kundu Chanchal, Sarkar Sumantra
Department of Pediatric Medicine, Medical College, Kolkata, 88 college street, Kolkata-700073, West Bengal, India
Department of Pediatric Medicine, Medical College, Kolkata, 88 college street, Kolkata-700073, West Bengal, India.
J Trop Pediatr. 2016 Feb;62(1):55-62. doi: 10.1093/tropej/fmv072. Epub 2015 Oct 28.
A prospective observational study was conducted in a tertiary care hospital to study clinicoepidemiological profile of potentially rabid animal bite cases from rural India. Total of 308 children (median age 6 years) admitted to hospital, were recruited over 1 year and followed up till completion of antirabies vaccine course. Dog was the commonest (77.27%) offending animal. Of the exposures, 66.88% were scratches, 88.96% were unprovoked and 27.27% were categorized as Class III. The median times to wound toileting and reporting to health facility were 1 and 6 h, respectively. Majority received prompt PEP in hospital, and RIG was administered in 34.55% of Class II and 90.48% of Class III exposures. Compared with their older counterparts, children aged <5 years suffered more bites on face and trunk and more Class III exposures. The rabies prophylaxis scenario is encouraging, when compared with earlier studies, but there are gaps to be addressed.
在一家三级护理医院进行了一项前瞻性观察研究，以研究印度农村地区潜在狂犬病动物咬伤病例的临床流行病学特征。在1年多的时间里，共招募了308名入院儿童（中位年龄6岁），并随访至完成狂犬病疫苗疗程。狗是最常见的致伤动物（77.27%）。在暴露情况中，抓伤占66.88%，无故暴露占88.96%，27.27%被归类为III级。伤口处理和报告至医疗机构的中位时间分别为1小时和6小时。大多数人在医院接受了及时的暴露后预防（PEP），34.55%的II级暴露和90.48%的III级暴露使用了狂犬病免疫球蛋白（RIG）。与年龄较大的儿童相比，<5岁的儿童面部和躯干咬伤更多，III级暴露也更多。与早期研究相比，狂犬病预防情况令人鼓舞，但仍有差距需要解决。
