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麻醉医生对心脏手术后风险调整死亡率的影响。

The contribution of the anaesthetist to risk-adjusted mortality after cardiac surgery.

作者信息

Papachristofi O, Sharples L D, Mackay J H, Nashef S A M, Fletcher S N, Klein A A

机构信息

MRC Biostatistics Unit, Institute of Public Health, Cambridge, UK.

Clinical Trials Research Unit, University of Leeds, Leeds, UK.

出版信息

Anaesthesia. 2016 Feb;71(2):138-46. doi: 10.1111/anae.13291. Epub 2015 Oct 28.

Abstract

It is widely accepted that the performance of the operating surgeon affects outcomes, and this has led to the publication of surgical results in the public domain. However, the effect of other members of the multidisciplinary team is unknown. We studied the effect of the anaesthetist on mortality after cardiac surgery by analysing data collected prospectively over ten years of consecutive cardiac surgical cases from ten UK centres. Casemix-adjusted outcomes were analysed in models that included random-effects for centre, surgeon and anaesthetist. All cardiac surgical operations for which the EuroSCORE model is appropriate were included, and the primary outcome was in-hospital death up to three months postoperatively. A total of 110 769 cardiac surgical procedures conducted between April 2002 and March 2012 were studied, which included 127 consultant surgeons and 190 consultant anaesthetists. The overwhelming factor associated with outcome was patient risk, accounting for 95.75% of the variation for in-hospital mortality. The impact of the surgeon was moderate (intra-class correlation coefficient 4.00% for mortality), and the impact of the anaesthetist was negligible (0.25%). There was no significant effect of anaesthetist volume above ten cases per year. We conclude that mortality after cardiac surgery is primarily determined by the patient, with small but significant differences between surgeons. Anaesthetists did not appear to affect mortality. These findings do not support public disclosure of cardiac anaesthetists' results, but substantially validate current UK cardiac anaesthetic training and practice. Further research is required to establish the potential effects of very low anaesthetic caseloads and the effect of cardiac anaesthetists on patient morbidity.

摘要

手术医生的表现会影响手术结果,这一点已得到广泛认可,这也促使手术结果在公共领域得以公布。然而,多学科团队中其他成员的影响尚不清楚。我们通过分析英国十个中心连续十年前瞻性收集的心脏手术病例数据,研究了麻醉医生对心脏手术后死亡率的影响。在包含中心、外科医生和麻醉医生随机效应的模型中分析了病例组合调整后的结果。纳入了所有适用于欧洲心脏手术风险评估系统(EuroSCORE)模型的心脏外科手术,主要结局是术后三个月内的院内死亡。研究了2002年4月至2012年3月期间进行的总共110769例心脏外科手术,其中包括127名顾问外科医生和190名顾问麻醉医生。与结局相关的压倒性因素是患者风险,占院内死亡率变异的95.75%。外科医生的影响适中(死亡率的组内相关系数为4.00%),而麻醉医生的影响可忽略不计(0.25%)。每年麻醉病例超过十例时,麻醉医生的工作量没有显著影响。我们得出结论,心脏手术后的死亡率主要由患者决定,外科医生之间存在虽小但显著的差异。麻醉医生似乎并未影响死亡率。这些发现不支持公开披露心脏麻醉医生的结果,但充分验证了英国目前的心脏麻醉培训和实践。需要进一步研究来确定极低麻醉病例量的潜在影响以及心脏麻醉医生对患者发病率的影响。

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