Payne David E, Boles Blaise R
Department of Microbiology, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA, USA.
Curr Genet. 2016 Feb;62(1):137-41. doi: 10.1007/s00294-015-0527-5. Epub 2015 Oct 29.
Bacterial cells are most often found in the form of multicellular aggregates commonly referred to as biofilms. Biofilms offer their member cells several benefits, such as resistance to killing by antimicrobials and predation. During biofilm formation there is a production of extracellular substances that, upon assembly, constitute an extracellular matrix. The ability to generate a matrix encasing the microbial cells is a common feature of biofilms, but there is diversity in matrix composition and in interaction between matrix components. The different components of bacterial biofilm extracellular matrixes, known as matrix interactions, and resulting implications are discussed in this review.
细菌细胞最常以多细胞聚集体的形式存在,通常被称为生物膜。生物膜为其成员细胞提供了多种益处,例如抵抗抗菌剂的杀灭和捕食。在生物膜形成过程中,会产生细胞外物质,这些物质组装后构成细胞外基质。生成包裹微生物细胞的基质的能力是生物膜的一个共同特征,但基质组成以及基质成分之间的相互作用存在多样性。本文综述了细菌生物膜细胞外基质的不同成分,即基质相互作用及其产生的影响。