Hammer Adam M, Morris Niya L, Cannon Abigail R, Shults Jill A, Curtis Brenda, Casey Carol A, Sueblinvong Viranuj, Persidsky Yuri, Nixon Kimberly, Brown Lou Ann, Waldschmidt Thomas, Mandrekar Pranoti, Kovacs Elizabeth J, Choudhry Mashkoor A
Alcohol Research Program, Burn and Shock Trauma Research Institute, Department of Surgery, Loyola University Chicago Health Sciences Campus, Maywood, IL, United States; Integrative Cell Biology Program, Loyola University Chicago Health Sciences Campus, Maywood, IL, United States.
Alcohol Research Program, Burn and Shock Trauma Research Institute, Department of Surgery, Loyola University Chicago Health Sciences Campus, Maywood, IL, United States.
Alcohol. 2015 Dec;49(8):767-72. doi: 10.1016/j.alcohol.2015.09.002. Epub 2015 Oct 8.
On November 21, 2014 the 19th annual Alcohol and Immunology Research Interest Group (AIRIG) meeting was held at Loyola University Chicago Health Sciences Campus in Maywood, Illinois. The meeting focused broadly on inflammatory cell signaling responses in the context of alcohol and alcohol-use disorders, and was divided into four plenary sessions focusing on the gut and liver, lung infections, general systemic effects of alcohol, and neuro-inflammation. One common theme among many talks was the differential roles of macrophages following both chronic and acute alcohol intoxication. Macrophages were shown to play significant roles in regulating inflammation, oxidative stress, and viral infection following alcohol exposure in the liver, lungs, adipose tissue, and brain. Other work examined the role of alcohol on disease progression in a variety of pathologies including psoriasis, advanced stage lung disease, and cancer.
2014年11月21日，第19届年度酒精与免疫研究兴趣小组（AIRIG）会议在伊利诺伊州梅伍德的芝加哥洛约拉大学健康科学园区举行。会议广泛聚焦于酒精及酒精使用障碍背景下的炎症细胞信号反应，并分为四个全会场，分别聚焦于肠道与肝脏、肺部感染、酒精的一般全身效应以及神经炎症。众多演讲中的一个共同主题是巨噬细胞在慢性和急性酒精中毒后的不同作用。研究表明，巨噬细胞在肝脏、肺部、脂肪组织和大脑中酒精暴露后调节炎症、氧化应激和病毒感染方面发挥着重要作用。其他研究探讨了酒精在包括牛皮癣、晚期肺病和癌症在内的多种病理疾病进展中的作用。
