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本文引用的文献

1
Alcohol, Aldehydes, Adducts and Airways.酒精、醛类、加合物与气道
Biomolecules. 2015 Nov 5;5(4):2987-3008. doi: 10.3390/biom5042987.
2
Effects of alcohol on intestinal epithelial barrier permeability and expression of tight junction-associated proteins.酒精对肠道上皮屏障通透性及紧密连接相关蛋白表达的影响。
Mol Med Rep. 2014 Jun;9(6):2352-6. doi: 10.3892/mmr.2014.2126. Epub 2014 Apr 9.
3
Acute alcohol intoxication prolongs neuroinflammation without exacerbating neurobehavioral dysfunction following mild traumatic brain injury.急性酒精中毒会延长神经炎症反应,而不会在轻度创伤性脑损伤后加剧神经行为功能障碍。
J Neurotrauma. 2014 Feb 15;31(4):378-86. doi: 10.1089/neu.2013.3093. Epub 2013 Dec 20.
4
Alcoholism causes alveolar macrophage zinc deficiency and immune dysfunction.酗酒可导致肺泡巨噬细胞锌缺乏和免疫功能障碍。
Am J Respir Crit Care Med. 2013 Sep 15;188(6):716-23. doi: 10.1164/rccm.201301-0061OC.
5
Nicotinic acetylcholine receptors are sensors for ethanol in lung fibroblasts.烟碱型乙酰胆碱受体是肺成纤维细胞中乙醇的传感器。
Alcohol Clin Exp Res. 2013 Jun;37(6):914-23. doi: 10.1111/acer.12044. Epub 2013 Feb 19.
6
Chronic alcohol exposure renders epithelial cells vulnerable to bacterial infection.慢性酒精暴露使上皮细胞容易受到细菌感染。
PLoS One. 2013;8(1):e54646. doi: 10.1371/journal.pone.0054646. Epub 2013 Jan 24.
7
Acute oral ethanol exposure triggers asthma in cockroach allergen-sensitized mice.急性口服乙醇暴露可引发蟑螂过敏原致敏的小鼠哮喘。
Am J Pathol. 2012 Sep;181(3):845-57. doi: 10.1016/j.ajpath.2012.05.020. Epub 2012 Jul 13.
8
Co-exposure to cigarette smoke and alcohol decreases airway epithelial cell cilia beating in a protein kinase Cε-dependent manner.香烟烟雾和酒精共同暴露以蛋白激酶 Cε 依赖的方式降低气道上皮细胞纤毛摆动。
Am J Pathol. 2012 Aug;181(2):431-40. doi: 10.1016/j.ajpath.2012.04.022. Epub 2012 Jun 5.
9
Alcohol reduces airway hyperresponsiveness (AHR) and allergic airway inflammation in mice.酒精可降低小鼠气道高反应性(AHR)和过敏性气道炎症。
Am J Physiol Lung Cell Mol Physiol. 2012 Feb 1;302(3):L308-15. doi: 10.1152/ajplung.00077.2011. Epub 2011 Nov 23.
10
Induction of innate immune genes in brain create the neurobiology of addiction.在大脑中诱导先天免疫基因会产生成瘾的神经生物学基础。
Brain Behav Immun. 2011 Jun;25 Suppl 1(Suppl 1):S4-S12. doi: 10.1016/j.bbi.2011.03.003. Epub 2011 Mar 21.

酒精与炎症反应:2015年酒精与免疫学研究兴趣小组(AIRIG)会议亮点

Alcohol and inflammatory responses: Highlights of the 2015 Alcohol and Immunology Research Interest Group (AIRIG) meeting.

作者信息

Cannon Abigail R, Morris Niya L, Hammer Adam M, Curtis Brenda, Remick Daniel G, Yeligar Samantha M, Poole Lauren, Burnham Ellen L, Wyatt Todd A, Molina Patricia E, So-Armah Kaku, Cisneros Trinidad, Wang Guoshun, Lang Charles H, Mandrekar Pranoti, Kovacs Elizabeth J, Choudhry Mashkoor A

机构信息

Department of Surgery, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, USA; Integrative Cell Biology Program, Loyola University Chicago Health Sciences Division, Maywood, IL, USA.

Department of Surgery, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, USA.

出版信息

Alcohol. 2016 Aug;54:73-7. doi: 10.1016/j.alcohol.2016.06.005. Epub 2016 Jul 25.

DOI:10.1016/j.alcohol.2016.06.005
PMID:27522326
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5003611/
Abstract

On September 27, 2015 the 20th annual Alcohol and Immunology Research Interest Group (AIRIG) meeting was held as a satellite symposium at the annual meeting of the Society for Leukocyte Biology in Raleigh, NC. The 2015 meeting focused broadly on adverse effects of alcohol and alcohol-use disorders in multiple organ systems. Divided into two plenary sessions, AIRIG opened with the topic of pulmonary inflammation as a result of alcohol consumption, which was followed by alcohol's effect on multiple organs, including the brain and liver. With presentations showing the diverse range of underlying pathology and mechanisms associated with multiple organs as a result of alcohol consumption, AIRIG emphasized the importance of continued alcohol research, as its detrimental consequences are not limited to one or even two organs, but rather extend to the entire host as a whole.

摘要

2015年9月27日,第20届酒精与免疫研究兴趣小组(AIRIG)年会作为卫星研讨会,在北卡罗来纳州罗利市举行的白细胞生物学学会年会上召开。2015年会议广泛聚焦于酒精及酒精使用障碍在多个器官系统中的不良影响。AIRIG会议分为两场全会,开场主题是饮酒导致的肺部炎症,随后是酒精对包括脑和肝在内的多个器官的影响。会上的报告展示了饮酒导致多个器官出现的各种潜在病理和机制,AIRIG强调了持续开展酒精研究的重要性,因为其有害后果不仅限于一两个器官,而是会扩展到整个机体。