Wang Xueqiang, Pi Yanling, Chen Binglin, Chen Peijie, Liu Yu, Wang Ru, Li Xin, Zhu Yi, Yang Yujie, Niu Zhanbin
Department of Sport Rehabilitation, Shanghai University of Sport, Shanghai, China.
Department of Rehabilitation Medicine, Shanghai Shangti Orthopaedic Hospital, Shanghai, China.
Sci Rep. 2015 Nov 3;5:15913. doi: 10.1038/srep15913.
Traditional Chinese exercise (TCE) has many uses in the prevention and treatment of chronic diseases. However, there is no consensus regarding the benefit of TCE for chronic diseases. Our objective is to examine the effect of TCE on the quality of life and depression for chronic diseases by performing a meta-analysis of randomized controlled trials (RCTs). We only cover published RCTs. The outcome measures included quality of life and depression. Sixty articles with a total of 4311 patients were included. The pooling revealed that TCE could improve the SF-36 physical function subscale in the short term [SMD (95% CI) = 0.35 (0.13, 0.56), P = 0.002] and mid-term [SMD (95% CI) = 0.49 (0.12, 0.85), P = 0.009], GHQ [SMD (95% CI) = -0.68 (-1.26, -0.09), P = 0.02], the Center for Epidemiologic Studies depression scale in the short term [SMD (95% CI) = -0.86 (-1.42, -0.31), P = 0.002] and mid-term [SMD (95% CI) = -0.41 (-0.64, -0.18), P < 0.001]. The meta-analysis of RCT demonstrates that TCE can significantly improve the quality of life and depression of patients with chronic diseases. These findings provide useful information for patients with chronic diseases as well as for medical staff.
传统中医运动（TCE）在慢性病的预防和治疗中有多种用途。然而，关于TCE对慢性病的益处尚无共识。我们的目标是通过对随机对照试验（RCT）进行荟萃分析，研究TCE对慢性病患者生活质量和抑郁的影响。我们仅纳入已发表的RCT。结局指标包括生活质量和抑郁。共纳入60篇文章，涉及4311名患者。汇总分析显示，TCE可在短期内[标准化均数差（SMD）（95%置信区间）=0.35（0.13，0.56），P=0.002]和中期[SMD（95%置信区间）=0.49（0.12，0.85），P=0.009]改善SF-36身体功能子量表，在短期内改善一般健康问卷[SMD（95%置信区间）=-0.68（-1.26，-0.09），P=0.02]，在短期内[SMD（95%置信区间）=-0.86（-1.42，-0.31），P=0.002]和中期[SMD（95%置信区间）=-0.41（-0.64，-0.18），P<0.001]改善流行病学研究中心抑郁量表。RCT的荟萃分析表明，TCE可显著改善慢性病患者的生活质量和抑郁状况。这些发现为慢性病患者以及医务人员提供了有用信息。
