Basso Davide, Ribero Simone, Blazek Claudia, Dietrich Nathalie, Beltraminelli Helmut, Ramelet Albert A, Borradori Luca, Adatto Maurice
Department of Dermatology, University Hospital Inselspital Bern, University of Bern, Bern, Switzerland.
Dermatology. 2016;232(1):107-11. doi: 10.1159/000439126. Epub 2015 Nov 4.
Cutaneous collagenous vasculopathy (CCV) is a rare idiopathic microangiopathy of the cutaneous vasculature characterized histologically by the presence of dilated small blood vessels with flat endothelial cells and thickened walls containing hyaline material in the upper dermis. We report an elderly patient presenting with an extensive form of CCV involving the trunk, upper and lower limbs. She was treated with Multiplex PDL 595-nm/Nd:YAG 1,064-nm laser and optimized pulsed light. This approach, which has never been reported for CCV so far, resulted in a striking and almost complete clearance of the widespread lesions. We here review our knowledge about CCV and therapeutic options available with a survey of the literature.
皮肤胶原性血管病（CCV）是一种罕见的皮肤血管特发性微血管病，组织学特征为真皮浅层存在扩张的小血管，内皮细胞扁平，管壁增厚，含有透明质物质。我们报告一名老年患者，患有累及躯干、上肢和下肢的广泛型CCV。她接受了595nm倍频Nd:YAG 1064nm激光和优化脉冲光治疗。这种方法迄今尚未见用于CCV的报道，却使广泛的皮损显著且几乎完全消退。我们在此通过文献综述回顾了我们对CCV的认识以及现有的治疗选择。
