Freitas Andréia Diane, Franzon Orli
Hospital Regional Homero de Miranda Gomes, Secretaria de Estado da Saúde, São José, SC, Brazil.
Arq Bras Cir Dig. 2015 Jul-Sep;28(3):163-6. doi: 10.1590/S0102-67202015000300004.
The lactate is a product of anaerobic metabolism; it can be used as a marker on demand and availability of oxygen. Changes in lactate levels can be effectively used as a marker in resuscitation maneuvers, even in patients with stable vital signs.
To verify the lactate clearance as a predictor of mortality in trauma patients, in need of intensive care.
A total of 851 patients were admitted in ICU, in which 146 were victims of multiple trauma; due to the exclusion criteria, were included 117.
Patients were 87% male, mean age 32.4 years, motorcycle drivers, Glasgow coma scale between 3-8, affected by cranial trauma, followed by abdominal trauma. Was verified mortality up to 48 h and global mortality, that did not show statistical relationship between lactate clearance and mortality (p=0.928).
There is no correlation between admission lactate or lactate clearance and mortality in patients treated with multiple trauma.
乳酸是无氧代谢的产物；它可作为氧气需求和可利用性的标志物。即使在生命体征稳定的患者中，乳酸水平的变化也能有效地用作复苏操作的标志物。
验证乳酸清除率作为需要重症监护的创伤患者死亡率的预测指标。
共有851例患者入住重症监护病房，其中146例为多发伤患者；由于排除标准，纳入117例。
患者87%为男性，平均年龄32.4岁，为摩托车驾驶者，格拉斯哥昏迷量表评分在3 - 8分之间，受颅脑创伤影响，其次是腹部创伤。验证了至48小时的死亡率和总体死亡率，乳酸清除率与死亡率之间未显示出统计学关系（p = 0.928）。
多发伤患者入院时的乳酸水平或乳酸清除率与死亡率之间无相关性。
