Heck E, Petty C, Palestine A, Luckenbach M, Salahuddin S Z, Nussenblatt R, Harris W, Baxter C, McCulley J
Transplant Services, University of Texas Southwestern Medical Center, Dallas 75235-9074.
Cornea. 1989;8(2):77-80.
The spread of AIDS and its association with a retrovirus, commonly called T-lymphotropic virus type III (HIV) has produced great concern among those involved in transplantation about the possibility for transmission of this disease through tissue and organ transplant. Isolation of the virus from conjunctiva and tears further heightened this concern for corneal transplants. This review of medical examiner (ME) cases, a population in which high numbers of transplant corneas are retrieved, has revealed positive serologic tests for HIV in serum from 5 cases in 205 screens. These represent potential donors based on other standard medical criteria available at the time of collection. This tissue was also submitted for viral culture, and virus was recovered from the corneal tissue in McCarey-Kaufman (MK) media. These findings and case reviews are discussed.
艾滋病的传播及其与一种逆转录病毒（通常称为III型嗜T淋巴细胞病毒，即HIV）的关联，引发了移植领域相关人员对这种疾病通过组织和器官移植传播可能性的高度关注。从结膜和泪液中分离出该病毒，进一步加剧了对角膜移植的担忧。本研究对法医（ME）病例进行了回顾，在这一群体中回收了大量移植角膜，结果显示在205次筛查中有5例血清HIV血清学检测呈阳性。根据采集时可用的其他标准医学标准，这些病例代表了潜在的供体。这些组织也被送去进行病毒培养，在麦凯里 - 考夫曼（MK）培养基中从角膜组织中分离出了病毒。本文对这些发现和病例回顾进行了讨论。
