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医院与法医鉴定病例中HIV抗体阳性眼/角膜捐献者的发生率。

Incidence of HIV antibody-positive eye/cornea donors in hospital versus medical examiner cases.

作者信息

Danneffel M B, Sugar A

机构信息

Michigan Eye-Bank and Transplantation Center, Ann Arbor.

出版信息

Cornea. 1990 Jul;9(3):271-2.

PMID:2373020
Abstract

We retrospectively examined Michigan Eye-Bank and Transplantation Center data on all eye/cornea donors in Michigan and Illinois for whom human immunodeficiency virus (HIV) antibody screening results were available. This was done to compare the HIV-antibody positive serology rate in hospital versus medical examiner donors. This population consisted of 3,783 donor records for the period January 1, 1986 through June 30, 1988--a 30-month period. Of these, 2,628 records were from hospital donors, and 1,155 were medical examiner cases. Of the 2,628 hospital donors, 22 (or 0.83%) tested positive for HIV antibody. Ten of the 1,155 medical examiner donors (or 0.87%) tested positive for HIV antibody. We examined donor demographics of gender, race, age, positive hepatitis B surface antigen, and residence for each group. The difference in the HIV antibody-positive rate between the two groups--hospital and medical examiner donors--is 0.04%, with a slightly higher rate in the medical examiner group. The chi-square was 0.0079, and the p-value was 0.928. We conclude that this difference is neither clinically nor statistically significant.

摘要

我们回顾性研究了密歇根眼库和移植中心有关密歇根州和伊利诺伊州所有有人类免疫缺陷病毒(HIV)抗体筛查结果的眼/角膜捐赠者的数据。这样做是为了比较医院捐赠者和法医捐赠者中HIV抗体阳性血清学比率。该人群包括1986年1月1日至1988年6月30日这30个月期间的3783份捐赠者记录。其中,2628份记录来自医院捐赠者,1155份是法医案例。在2628名医院捐赠者中,22人(或0.83%)HIV抗体检测呈阳性。1155名法医捐赠者中有10人(或0.87%)HIV抗体检测呈阳性。我们检查了每组捐赠者的性别、种族、年龄、乙肝表面抗原阳性情况和居住地等人口统计学特征。两组(医院捐赠者和法医捐赠者)之间的HIV抗体阳性率差异为0.04%,法医组的比率略高。卡方值为0.0079,p值为0.928。我们得出结论,这种差异在临床和统计学上均无显著意义。

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