Lin Feng, Xiao Zhilan, Mei Jiandong, Liu Chengwu, Pu Qiang, Ma Lin, Liao Hu, Guo Chenglin, Zhu Yunke, Zhao Yongsheng, Li Chuan, Li Jian, Liu Lunxu
Department of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu 610041, China.
J Thorac Dis. 2015 Sep;7(9):1637-42. doi: 10.3978/j.issn.2072-1439.2015.09.09.
The management of synchronous thymic and pulmonary lesions remains a challenge due to the lack of case series and surgical guidelines. This study aims to retrospectively review our preliminary experience and results of performing simultaneous thoracoscopic resection of coexisting diseases of the lung and thymus.
Simultaneous thoracoscopic resection was performed to remove coexisting thymic and pulmonary lesions in nine patients from August 2008 to November 2013. Patient demographics, preoperative assessment, surgical procedures and postoperative course of these patients were reviewed.
There were four female and five male patients between 43 and 70 years old (median age, 64 years). Each patient had thymic neoplasm and solitary pulmonary lesion on chest computed tomography (CT) scan. Four patients underwent thoracoscopic lobectomy and thymectomy. One patient had thoracoscopic bronchovascular sleeve lobectomy combined with thymic cyst resection (TCR). The other four patients received pulmonary wedge resection and thymectomy (n=3)/TCR (n=1). The operation lasted from 35-480 min (median, 110 min). Intra-operative blood loss was 20-380 mL (median, 120 mL). Two patients developed post-operative pneumonia without mortality. All the patients were discharged home within 9 days after surgery. Two patients died from metastatic lung cancer 14 months after surgery.
Simultaneous thoracoscopic resection of coexisting pulmonary and thymic lesions is safe and feasible in selected patients.
由于缺乏病例系列报道和手术指南,同步性胸腺和肺部病变的处理仍然是一项挑战。本研究旨在回顾性分析我们同期进行胸腔镜下切除肺部和胸腺并存疾病的初步经验及结果。
2008年8月至2013年11月,对9例患者同期行胸腔镜下切除并存的胸腺和肺部病变。回顾了这些患者的人口统计学资料、术前评估、手术过程及术后病程。
9例患者中,女性4例,男性5例,年龄43至70岁(中位年龄64岁)。胸部计算机断层扫描(CT)显示每位患者均有胸腺肿瘤和孤立性肺部病变。4例行胸腔镜下肺叶切除术加胸腺切除术。1例行胸腔镜下支气管血管袖式肺叶切除术联合胸腺囊肿切除术(TCR)。另外4例行肺楔形切除术加胸腺切除术(3例)/TCR(1例)。手术时间为35至480分钟(中位时间110分钟)。术中失血20至380毫升(中位值120毫升)。2例患者发生术后肺炎,无死亡病例。所有患者术后9天内出院。2例患者术后14个月死于肺癌转移。
对于部分患者,同期胸腔镜下切除并存的肺部和胸腺病变安全可行。