Department of Biochemistry and Chemistry, University of Colorado, Boulder, CO 80309, USA.
Department of Biochemistry and Chemistry, University of Colorado, Boulder, CO 80309, USA; Howard Hughes Medical Institute, University of Colorado, Boulder, CO 80309, USA.
Cell. 2015 Nov 5;163(4):796-8. doi: 10.1016/j.cell.2015.10.056.
Two studies by Meyer et al. and Wang et al. demonstrate a role for m(6)A modification of mRNA in stimulating translation initiation. These findings add to the growing number of diverse mechanisms for translation initiation in eukaryotes.
迈尔等人和王等人的两项研究表明,mRNA 的 m(6)A 修饰在刺激翻译起始中发挥作用。这些发现增加了真核生物中翻译起始的多种不同机制。