Gaeini Zahra, Bahadoran Zahra, Malmir Hanieh, Mirmiran Parvin
Nutrition and Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, P.O. Box: 19395-4763, No. 24, Shahid-Erabi St., Yeman St., Velenjak, Tehran, Iran.
, Micronutrient Research Center, Research Institute for Endocrine Disorders, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
BMC Nutr. 2025 Jun 6;11(1):113. doi: 10.1186/s40795-025-01090-6.
Coconut oil has been suggested as a potential dietary intervention for weight management. However, the evidence regarding the effects of coconut oil supplementation on anthropometric measures (body weight, body mass index (BMI) and waist circumference (WC)) remains inconclusive.
we aimed to assess the overall effect of coconut oil supplementation on these anthropometric parameters and explore potential sources of heterogeneity.
We comprehensively searched electronic databases using appropriate keywords. We included 15 studies with the following criteria: (1) clinical trials in adults, with parallel or cross-over design, (2) evaluated the effect of coconut oil on body weight, BMI or WC, (3) compared the effect of a specific dose of coconut oil against a coconut oil-free diet or other types of oils, (4) considered the change in anthropometric parameters as the primary or one of the secondary outcomes, (5) provided mean and standard deviation (SD) of change in anthropometric parameters across study arms, (6) reported the number of participants in each study arm.
The trials included 620 participants and assessed the effects of coconut oil supplementation on body weight, BMI and WC. Our meta-analysis revealed statistically significant effects of coconut oil supplementation on weight and BMI, with mean differences of 0.04 kg (95% CI: 0.01 to 0.08 kg) and 0.01 kg/m2 (95% CI: 0.00 to 0.02). However, the effects were not clinically meaningful. There was no significant effect of coconut oil on WC. Subgroup analyses suggested that the duration of the intervention may influence the effect of coconut oil on body weight. In the sensitivity analysis, we found that the result of one study influenced the associations between coconut oil supplementation and weight or BMI.
Overall, our findings suggest no clinically significant effects of coconut oil supplementation on weight loss. Further research is needed to clarify the issue.
PROSPERO CRD420251031291.
椰子油已被认为是一种潜在的用于体重管理的饮食干预措施。然而，关于补充椰子油对人体测量指标（体重、体重指数（BMI）和腰围（WC））影响的证据仍然不明确。
我们旨在评估补充椰子油对这些人体测量参数的总体影响，并探索潜在的异质性来源。
我们使用适当的关键词全面检索了电子数据库。我们纳入了15项研究，其符合以下标准：（1）针对成年人的临床试验，采用平行或交叉设计；（2）评估椰子油对体重、BMI或WC的影响；（3）比较特定剂量的椰子油与无椰子油饮食或其他类型油的效果；（4）将人体测量参数的变化视为主要或次要结局之一；（5）提供各研究组人体测量参数变化的均值和标准差（SD）；（6）报告每个研究组的参与者数量。
这些试验纳入了620名参与者，评估了补充椰子油对体重、BMI和WC的影响。我们的荟萃分析显示，补充椰子油对体重和BMI有统计学意义的影响，平均差异分别为0.04千克（95%CI：0.01至0.08千克）和0.01千克/平方米（95%CI：0.00至0.02）。然而，这些影响在临床上并无意义。椰子油对WC没有显著影响。亚组分析表明，干预持续时间可能会影响椰子油对体重的影响。在敏感性分析中，我们发现一项研究的结果影响了补充椰子油与体重或BMI之间的关联。
总体而言，我们的研究结果表明补充椰子油对减肥没有临床上的显著效果。需要进一步研究来阐明这一问题。
PROSPERO CRD420251031291。
