Applewhite Megan K, James Benjamin C, Kaplan Sharone P, Angelos Peter, Kaplan Edwin L, Grogan Raymon H, Aschebrook-Kilfoy Briseis
Endocrine Surgery Research Group, Department of Surgery, The University of Chicago, 5841 S. Maryland Ave. MC 4052, Chicago, IL, 60637, USA.
Division of Epidemiology, Department of Health Studies, The University of Chicago, 5841 S. Maryland Ave. MC 2007, N112, Chicago, IL, 60637, USA.
World J Surg. 2016 Mar;40(3):551-61. doi: 10.1007/s00268-015-3300-5.
The incidence of thyroid cancer is increasing. As such, the number of survivors is rising, and it has been shown that their quality of life (QOL) is worse than expected. Using results from the North American Thyroid Cancer Survivorship Study (NATCSS), a large-scale survivorship study, we aim to compare the QOL of thyroid cancer survivors to the QOL of survivors of other types of cancer.
The NATCSS assessed QOL overall and in four subcategories: physical, psychological, social, and spiritual well-being using the QOL-Cancer Survivor (QOL-CS) instrument. Studies that used the QOL-CS to evaluate survivors of other types of cancers were compared to the NATCSS findings using two-tailed t tests.
We compared results from NATCSS to QOL survivorship studies in colon, glioma, breast, and gynecologic cancer. The mean overall QOL in NATCSS was 5.56 (on a scale of 0-10, where 10 is the best). Overall QOL of patients with thyroid cancer was similar to that of patients with colon cancer (mean 5.20, p = 0.13), glioma (mean 5.96, p = 0.23), and gynecologic cancer (mean 5.59, p = 0.43). It was worse than patients surveyed with breast cancer (mean 6.51, p < 0.01).
We found the self-reported QOL of thyroid cancer survivors in our study population is overall similar to or worse than that of survivors of other types of cancer surveyed with the same instrument. This should heighten awareness of the significance of a thyroid cancer diagnosis and highlights the need for further research in how to improve care for this enlarging group of patients.
甲状腺癌的发病率正在上升。因此，幸存者的数量也在增加，并且已经表明他们的生活质量（QOL）比预期的要差。利用北美甲状腺癌幸存者研究（NATCSS）的结果，一项大规模的幸存者研究，我们旨在将甲状腺癌幸存者的生活质量与其他类型癌症幸存者的生活质量进行比较。
NATCSS使用生活质量-癌症幸存者（QOL-CS）工具全面评估生活质量以及身体、心理、社会和精神健康四个子类别。使用QOL-CS评估其他类型癌症幸存者的研究与NATCSS的结果通过双尾t检验进行比较。
我们将NATCSS的结果与结肠癌、神经胶质瘤、乳腺癌和妇科癌症的生活质量幸存者研究进行了比较。NATCSS中的平均总体生活质量为5.56（范围为0至10，其中10为最佳）。甲状腺癌患者的总体生活质量与结肠癌患者（平均5.20，p = 0.13）、神经胶质瘤患者（平均5.96，p = 0.23）和妇科癌症患者（平均5.59，p = 0.43）相似。它比乳腺癌患者（平均6.51，p < 0.
