Conservative Dentistry and Endodontics, Nair Hospital Dental College, Mumbai, Maharashtra, India.
School of Information, University of Michigan, Ann Arbor, MI, United States of America.
PeerJ. 2024 Oct 31;12:e18198. doi: 10.7717/peerj.18198. eCollection 2024.
The aim of this systematic review and meta-analysis was to furnish evidence-based recommendations for the utilization of bioceramic-based and resin-based sealers in clinical endodontics, with a focus on reducing postoperative discomfort.
The investigation's methodology was registered on the International Prospective Database of Systematic Reviews (PROSPERO: CRD42022355506) and executed using the 2020 PRISMA protocol. Articles were selected utilizing the PICO technique and applying specific inclusion and exclusion criteria. Articles published between January 2000 and August 2022, PubMed, MEDLINE, and DOAJ were utilized as primary data sources. After the identification of studies, two autonomous reviewers evaluated the titles and abstracts, and data from qualifying studies were extracted.
Nine published studies were included in this analysis. The findings indicate that there were no significant differences in the Visual Analog Scale (VAS) scores between resin-based and bioceramic root canal sealers at intervals of 6 hours, 12 hours, 24 hours, and 48 hours after treatment.
The findings of this systematic review and meta-analysis suggest that after the utilization of bioceramic sealers during root canal therapy, the pain and discomfort levels were not significantly different from those experienced pain after the use of resin-based sealers.
本系统评价和荟萃分析的目的是为临床牙髓病学中使用基于生物陶瓷和基于树脂的密封剂提供循证建议，重点是减少术后不适。
该研究的方法在国际前瞻性系统评价数据库（PROSPERO：CRD42022355506）上进行了注册，并使用 2020 年 PRISMA 方案进行了执行。采用 PICO 技术选择文章，并应用特定的纳入和排除标准。研究的主要数据来源是 2000 年 1 月至 2022 年 8 月的 PubMed、MEDLINE 和 DOAJ 上发表的文章。在确定研究后，两名独立评审员评估了标题和摘要，并提取了合格研究的数据。
本分析共纳入 9 项已发表的研究。研究结果表明，在治疗后 6 小时、12 小时、24 小时和 48 小时，基于树脂和基于生物陶瓷的根管密封剂的视觉模拟量表（VAS）评分之间没有显著差异。
本系统评价和荟萃分析的结果表明，在根管治疗中使用生物陶瓷密封剂后，疼痛和不适程度与使用树脂基密封剂后疼痛程度没有显著差异。
