Baraldi Olga, Valentini Chiara, Donati Gabriele, Comai Giorgia, Cuna Vania, Capelli Irene, Angelini Maria Laura, Moretti Maria Ilaria, Angeletti Andrea, Piscaglia Fabio, La Manna Gaetano
Olga Baraldi, Chiara Valentini, Gabriele Donati, Giorgia Comai, Vania Cuna, Irene Capelli, Maria Laura Angelini, Maria Ilaria Moretti, Andrea Angeletti, Gaetano La Manna, Department of Experimental, Diagnostic, Specialty Medicine, Nephrology, Dialysis, and Renal Transplant Unit, S. Orsola University Hospital, 40138 Bologna, Italy.
World J Nephrol. 2015 Nov 6;4(5):511-20. doi: 10.5527/wjn.v4.i5.511.
Acute kidney injury (AKI) is a common complication in patients with end-stage liver disease and advanced cirrhosis regardless of the underlying cause. Hepatorenal syndrome (HRS), a functional form of kidney failure, is one of the many possible causes of AKI. HRS is potentially reversible but involves highly complex pathogenetic mechanisms and equally complex clinical and therapeutic management. Once HRS has developed, it has a very poor prognosis. This review focuses on the diagnostic approach to HRS and discusses the therapeutic protocols currently adopted in clinical practice.
急性肾损伤（AKI）是终末期肝病和晚期肝硬化患者常见的并发症，无论其潜在病因如何。肝肾综合征（HRS）是一种功能性肾衰竭，是AKI众多可能病因之一。HRS可能是可逆的，但涉及高度复杂的发病机制以及同样复杂的临床和治疗管理。一旦HRS发生，其预后非常差。本综述重点关注HRS的诊断方法，并讨论目前临床实践中采用的治疗方案。
