Raber Jeffrey C, Elzinga Sytze, Kaplan Charles
The Werc Shop, LLC, USA.
J Toxicol Sci. 2015 Dec;40(6):797-803. doi: 10.2131/jts.40.797.
Cannabis concentrates are gaining rapid popularity in the California medical cannabis market. These extracts are increasingly being consumed via a new inhalation method called 'dabbing'. The act of consuming one dose is colloquially referred to as "doing a dab". This paper investigates cannabinoid transfer efficiency, chemical composition and contamination of concentrated cannabis extracts used for dabbing. The studied concentrates represent material available in the California medical cannabis market. Fifty seven (57) concentrate samples were screened for cannabinoid content and the presence of residual solvents or pesticides. Considerable residual solvent and pesticide contamination were found in these concentrates. Over 80% of the concentrate samples were contaminated in some form. THC max concentrations ranged from 23.7% to 75.9% with the exception of one outlier containing 2.7% THC and 47.7% CBD. Up to 40% of the theoretically available THC could be captured in the vapor stream of a dab during inhalation experiments. Dabbing offers immediate physiological relief to patients in need but may also be more prone to abuse by recreational users seeking a more rapid and intense physiological effect.
大麻浓缩物在加利福尼亚医用大麻市场迅速流行起来。这些提取物越来越多地通过一种名为“滴吸”的新吸入方法被消费。吸食一剂的行为通俗地称为“来一口”。本文研究了用于滴吸的浓缩大麻提取物的大麻素转移效率、化学成分和污染情况。所研究的浓缩物代表了加利福尼亚医用大麻市场上可得的材料。对57个浓缩物样本进行了大麻素含量以及残留溶剂或农药存在情况的筛查。在这些浓缩物中发现了相当程度的残留溶剂和农药污染。超过80%的浓缩物样本受到了某种形式的污染。四氢大麻酚(THC)的最高浓度范围为23.7%至75.9%,但有一个异常样本含有2.7%的THC和47.7%的大麻二酚(CBD)除外。在吸入实验中,高达40%的理论可得THC可在一次滴吸的蒸气流中被捕获。滴吸能为有需要的患者提供即时的生理缓解,但也可能更容易被寻求更快、更强生理效果的娱乐性使用者滥用。