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上颌侧切牙的双重胚胎起源：对唇腭裂患者的临床意义

Dual embryonic origin of maxillary lateral incisors: clinical implications in patients with cleft lip and palate.

作者信息

Garib Daniela Gamba, Rosar Julia Petruccelli, Sathler Renata, Ozawa Terumi Okada

机构信息

School of Dentistry, Universidade de São Paulo, Bauru, São Paulo, Brazil.

Hospital for Rehabilitation of Craniofacial Anomalies, Universidade de São Paulo, Bauru, São Paulo, Brazil.

出版信息

Dental Press J Orthod. 2015 Oct;20(5):118-25. doi: 10.1590/2177-6709.20.5.118-125.sar.

DOI:10.1590/2177-6709.20.5.118-125.sar
PMID:26560830
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4644928/
Abstract

INTRODUCTION

Cleft lip and palate are craniofacial anomalies highly prevalent in the overall population. In oral clefts involving the alveolar ridge, variations of number, shape, size and position are observed in maxillary lateral incisors. The objective of this manuscript is to elucidate the embryonic origin of maxillary lateral incisors in order to understand the etiology of these variations.Contextualization: The hypothesis that orofacial clefts would split maxillary lateral incisor buds has been previously reported. However, recent studies showed that maxillary lateral incisors have dual embryonic origin, being partially formed by both the medial nasal process and the maxillary process. In other words, the mesial half of the lateral incisor seems to come from the medial nasal process while the distal half of the lateral incisor originates from the maxillary process. In cleft patients, these processes do not fuse, which results in different numerical and positional patterns for lateral incisors relating to the alveolar cleft. In addition to these considerations, this study proposes a nomenclature for maxillary lateral incisors in patients with cleft lip and palate, based on embryology and lateral incisors position in relation to the alveolar cleft.

CONCLUSION

Embryological knowledge on the dual origin of maxillary lateral incisors and the use of a proper nomenclature for their numerical and positional variations renders appropriate communication among professionals and treatment planning easier, in addition to standardizing research analysis.

摘要

引言

唇腭裂是在整个人口中高度普遍的颅面畸形。在涉及牙槽嵴的口腔裂隙中，上颌侧切牙在数量、形状、大小和位置上存在变异。本手稿的目的是阐明上颌侧切牙的胚胎起源，以便了解这些变异的病因。

背景

先前已有报道提出口面部裂隙会分裂上颌侧切牙牙胚的假说。然而，最近的研究表明，上颌侧切牙有双重胚胎起源，部分由内侧鼻突和上颌突共同形成。换句话说，侧切牙的近中半部分似乎来自内侧鼻突，而侧切牙的远中半部分起源于上颌突。在腭裂患者中，这些突起没有融合，这导致侧切牙与牙槽裂相关的数量和位置模式不同。除了这些考虑因素外，本研究还基于胚胎学以及侧切牙相对于牙槽裂的位置，为唇腭裂患者的上颌侧切牙提出了一种命名法。

结论

关于上颌侧切牙双重起源的胚胎学知识以及对其数量和位置变异使用恰当的命名法，除了使研究分析标准化外，还能让专业人员之间的沟通更加顺畅，并便于治疗计划的制定。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/843e/4644928/b3dd9f55dd0b/2176-9451-dpjo-20-05-00118-gf06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/843e/4644928/07e07b387a5d/2176-9451-dpjo-20-05-00118-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/843e/4644928/b9dd69283edb/2176-9451-dpjo-20-05-00118-gf02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/843e/4644928/b9aa9bfe1dee/2176-9451-dpjo-20-05-00118-gf03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/843e/4644928/7ec4bf941df2/2176-9451-dpjo-20-05-00118-gf04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/843e/4644928/abb498749bb3/2176-9451-dpjo-20-05-00118-gf05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/843e/4644928/b3dd9f55dd0b/2176-9451-dpjo-20-05-00118-gf06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/843e/4644928/07e07b387a5d/2176-9451-dpjo-20-05-00118-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/843e/4644928/b9dd69283edb/2176-9451-dpjo-20-05-00118-gf02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/843e/4644928/b9aa9bfe1dee/2176-9451-dpjo-20-05-00118-gf03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/843e/4644928/7ec4bf941df2/2176-9451-dpjo-20-05-00118-gf04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/843e/4644928/abb498749bb3/2176-9451-dpjo-20-05-00118-gf05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/843e/4644928/b3dd9f55dd0b/2176-9451-dpjo-20-05-00118-gf06.jpg

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Am J Orthod Dentofacial Orthop. 2015 Feb;147(2):205-13. doi: 10.1016/j.ajodo.2014.10.027.
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Is the presence of Simonart's band in patients with complete unilateral cleft lip and palate associated with the prevalence of missing maxillary lateral incisors?单侧完全性唇腭裂患者中存在西蒙氏条带与上颌侧切牙缺失的患病率是否相关？
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