Yoshikawa Hiroo
Division of Neurology, Department of Internal Medicine, Hyogo College of Medicine.
Brain Nerve. 2015 Nov;67(11):1305-11. doi: 10.11477/mf.1416200300.
The epidemiologic features of the Guillain-Barré syndrome (GBS) have been reported from North America, England, Iceland, and Norway before 1979. The population incidence rates of GBS fulfilling the NINCDS (National Institute of Neurological and Communicative Disorders and Stroke) criteria in USA, Canada, Italy, Spain, and Sweden ranged from 0.62 cases to 2.66 cases per 100,000 person-years across all age groups, with a relative risk of 1.78 for males. GBS incidence increased by 20% for every 10-year increase in age. In Japan, the incidence of GBS was 1.15 per 100,000 person-years. Males were affected 1.5 times more frequently than females. The average age of patients with GBS was 39.1 ± 20.0 years, which is lesser than that in North America and Europe. The relative ratio of the occurrence of Fisher syndrome among patients with GBS was higher than that in other Asian countries.
1979年以前，北美、英国、冰岛和挪威曾报道过吉兰-巴雷综合征（GBS）的流行病学特征。在美国、加拿大、意大利、西班牙和瑞典，符合美国国立神经疾病和中风研究所（NINCDS）标准的GBS人群发病率在所有年龄组中为每10万人年0.62例至2.66例，男性的相对风险为1.78。GBS发病率随年龄每增加10岁上升20%。在日本，GBS发病率为每10万人年1.15例。男性受影响的频率是女性的1.5倍。GBS患者的平均年龄为39.1±20.0岁，低于北美和欧洲。GBS患者中费舍尔综合征的相对发生率高于其他亚洲国家。
