Rivera-Lillo Gonzalo, Torres-Castro Rodrigo, Burgos Pablo I, Varas-Díaz Gonzalo, Vera-Uribe Roberto, Puppo Homero, Hernández Mauricio
Department of Physical Therapy, Faculty of Medicine, University of Chile, Santiago de Chile, Chile.
Clínica Los Coihues, Center of Integrated Studies in Neurorehabilitation, Santiago de Chile, Chile.
J Peripher Nerv Syst. 2016 Dec;21(4):339-344. doi: 10.1111/jns.12182.
The Guillain-Barré syndrome (GBS) incidence rate (IR) varies between 0.16 and 3.00 cases per 100,000 inhabitants. Little data exist on the epidemiology of GBS in Latin American countries. Our objective was to describe GBS epidemiology based on a national database in a Latin American country and to contribute to the global map of GBS epidemiology. This was a retrospective study that included all reported GBS cases in Chile between 2001 and 2012. Gender, age, seasonal occurrence, and geographical distribution were analyzed. A total of 4,158 GBS cases were identified from 19,513,655 registries. The mean age was 37 ± 24 years, and 59% of patients were male (male to female ratio of 1.5 : 1). Gender IR was 2.53/100,000 for males and 1.68/100,000 for females. The overall standardized IR was 2.1/100,000, although this varied between 1.61/100,000 (2001) and 2.35/100,000 (2010). The seasonal distribution was as follows: autumn 22%; winter 25%; spring 27%; and summer 26%. The geographical IR were as follows: far North 1.49/100,000; North 1.94/100,000; Central 1.97/100,000; South 3.18/100,000; and far South 2.78/100,000. The reported IR of GBS in Chile was similar to other studies based on national databases. In Chile, IR was greater in men and in the south.
吉兰-巴雷综合征（GBS）的发病率为每10万居民中有0.16至3.00例。关于拉丁美洲国家GBS流行病学的数据很少。我们的目的是根据拉丁美洲一个国家的全国数据库描述GBS的流行病学情况，并为GBS流行病学的全球地图做出贡献。这是一项回顾性研究，纳入了2001年至2012年智利所有报告的GBS病例。分析了性别、年龄、季节发病情况和地理分布。从19513655份登记记录中总共确定了4158例GBS病例。平均年龄为37±24岁，59%的患者为男性（男女比例为1.5:1）。男性的性别发病率为2.53/10万，女性为1.68/10万。总体标准化发病率为2.1/10万，不过在2001年（1.61/10万）和2010年（2.35/10万）之间有所变化。季节分布如下：秋季22%；冬季25%；春季27%；夏季26%。地理发病率如下：最北部1.49/10万；北部1.94/10万；中部1.97/10万；南部3.18/10万；最南部2.78/10万。智利报告的GBS发病率与其他基于全国数据库的研究相似。在智利，男性和南部的发病率更高。
