来自海葵赫氏海葵的吲哚生物碱和来自蓝环章鱼的高肌氨酸。

Indole Alkaloids from the Sea Anemone Heteractis aurora and Homarine from Octopus cyanea.

作者信息

Shaker Kamel H, Göhl Matthias, Müller Tobias, Seifert Karlheinz

机构信息

Chemistry Department, College of Science, King Khalid University, Abha, Saudia Arabia.

Department of Organic Chemistry, NW II, University of Bayreuth, DE-95440 Bayreuth, (phone: +49-921-553098; fax: +49-921-555358).

出版信息

Chem Biodivers. 2015 Nov;12(11):1746-55. doi: 10.1002/cbdv.201400406.

DOI:10.1002/cbdv.201400406

PMID:26567952

Abstract

The two new indole alkaloids 2-amino-1,5-dihydro-5-(1H-indol-3-ylmethyl)-4H-imidazol-4-one (1), 2-amino-5-[(6-bromo-1H-indol-3-yl)methyl]-3,5-dihydro-3-methyl-4H-imidazol-4-one (2), and auramine (3) have been isolated from the sea anemone Heteractis aurora. Both indole alkaloids were synthesized for the confirmation of the structures. Homarine (4), along with uracil (5), hypoxanthine (6), and inosine (7) have been obtained from Octopus cyanea.

摘要

从海葵赫氏海葵中分离出了两种新的吲哚生物碱

2-氨基-1,5-二氢-5-(1H-吲哚-3-基甲基)-4H-咪唑-4-酮（1）、2-氨基-5-[(6-溴-1H-吲哚-3-基)甲基]-3,5-二氢-3-甲基-4H-咪唑-4-酮（2）以及金胺（3）。为了确定结构，合成了这两种吲哚生物碱。从蓝环章鱼中获得了高甜菜碱（4）以及尿嘧啶（5）、次黄嘌呤（6）和肌苷（7）。