Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province, School of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, PR China.
Laboratoire de Physique et Chimie de Nano-Objets, INSA, CNRS, Université de Toulouse, 135 Avenue de Rangueil, 31077 Toulouse, France.
Biosens Bioelectron. 2016 Mar 15;77:1112-8. doi: 10.1016/j.bios.2015.10.088. Epub 2015 Oct 31.
A novel polypyrrole (PPy) and graphene quantum dots (GQDs) @ Prussian Blue (PB) nanocomposite has been grafted on a graphite felt (GF) substrate (PPy/GQDs@PB/GF), and has been proven to be an efficient electrochemical sensor for the determination of l-cysteine (l-cys). GQDs, which were fabricated by carbonization of citric acid and adsorbed on GF surface ultrasonically, played an important role for promoting the synthesis process of PB via a spontaneous redox reaction between Fe(3+) and Fe(CN)6. The PPy film has been electro-polymerized to improve the electrochemical stability of the PPy/GQDs@PB/GF electrode. The as-prepared electrode was characterized by scanning electron microscopy (SEM), transmission electron microscopy (TEM), infrared spectroscopy (IR), X-ray diffraction (XRD) and electrochemical methods. It exhibited an excellent activity for the electrocatalytic oxidation of l-cys, with a detection sensitivity equal to 0.41 Amol(-1) L for a concentration range of 0.2-50 μmolL(-1), and equal to 0.15 Amol(-1) L for a concentration range of 50-1000 μmolL(-1). A low detection limit of 0.15 μmolL(-1), as well as a remarkable long-time stability and a negligible sensitivity to interfering analytes, were also ascertained.
一种新型的聚吡咯（PPy）和石墨烯量子点（GQDs）@普鲁士蓝（PB）纳米复合材料已被接枝到石墨毡（GF）基底上（PPy/GQDs@PB/GF），并已被证明是一种用于测定 l-半胱氨酸（l-cys）的有效电化学传感器。GQDs 是通过柠檬酸的碳化和超声吸附在 GF 表面上制备的，在 Fe（3+）和 [Fe（CN）6]（3-）之间的自发氧化还原反应中，对 PB 的合成过程起到了重要的促进作用。PPy 薄膜已被电化学聚合，以提高 PPy/GQDs@PB/GF 电极的电化学稳定性。所制备的电极通过扫描电子显微镜（SEM）、透射电子显微镜（TEM）、红外光谱（IR）、X 射线衍射（XRD）和电化学方法进行了表征。它对 l-cys 的电催化氧化表现出优异的活性，检测灵敏度等于 0.2-50 μmolL（-1）浓度范围内的 0.41 Amol（-1）L，等于 50-1000 μmolL（-1）浓度范围内的 0.15 Amol（-1）L。还确定了低检测限为 0.15 μmolL（-1），以及显著的长时间稳定性和对干扰分析物的可忽略的灵敏度。
