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药物的鼻腔吸收机制。

Mechanism of nasal absorption of drugs.

作者信息

Hussain A A

机构信息

College of Pharmacy, University of Kentucky, Lexington 40536-0082.

出版信息

Prog Clin Biol Res. 1989;292:261-72.

PMID:2657766
Abstract

In recent years, nasal absorption has received a great deal of attention as a convenient and reliable method for the administration of certain drugs. Although this route is currently being used for the systemic administration of drugs, such as Oxytocin and DDAVP, it has only recently been quantitatively studied. This chapter will deal with the importance of the physical and chemical properties of drugs on the rate and extent of their nasal absorption.

摘要

近年来,鼻腔吸收作为一种方便可靠的某些药物给药方法受到了广泛关注。尽管目前该途径正用于如催产素和去氨加压素等药物的全身给药,但直到最近才对其进行定量研究。本章将探讨药物的物理和化学性质对其鼻腔吸收速率和程度的重要性。

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