Department of Orthopaedic Surgery, Institut Jules. Bordet, Université Libre de Bruxelles, Brussels, Belgium.
Department of Medicine, CHU Brugmann, Université Libre de Bruxelles, Brussels, Belgium.
J Bone Oncol. 2015 May 16;4(2):42-6. doi: 10.1016/j.jbo.2015.05.001. eCollection 2015 Jun.
Gorham-Stout disease is a rare disease characterized by anarchic lymphovascular proliferation causing resorption of bone sometimes leading to disastrous complications. Bone tissue is progressively replaced by angiomatic and lymphangiomatic tissue and finally by fibrous tissue. This disease is known to be ubiquitous and of complex etiology. We present a case of Gorham-Stout disease of the proximal fibula invading the proximal tibia and soft tissues of the popliteal space that was successfully treated with radiotherapy and zoledronic acid.
戈勒姆-斯图特病是一种罕见疾病,其特征为无秩序的淋巴管和血管增生,导致骨吸收,有时会导致灾难性的并发症。骨组织逐渐被血管和淋巴管组织以及纤维组织所取代。这种疾病被认为是无处不在的,病因复杂。我们报告了一例腓骨近端戈勒姆-斯图特病侵犯胫骨近端和腘窝软组织的病例,该病例经放疗和唑来膦酸治疗后取得了成功。