蜂毒对导致炎症性疾病的纤维化的保护作用。
The protective effect of bee venom on fibrosis causing inflammatory diseases.
作者信息
Lee Woo-Ram, Pak Sok Cheon, Park Kwan-Kyu
机构信息
Department of Pathology, College of Medicine, Catholic University of Daegu, 3056-6, Daemyung-4-Dong, Nam-gu, Daegu 705-718, Korea.
School of Biomedical Sciences, Charles Sturt University, Panorama Avenue, Bathurst, NSW 2795, Australia.
出版信息
Toxins (Basel). 2015 Nov 16;7(11):4758-72. doi: 10.3390/toxins7114758.
Abstract
Bee venom therapy is a treatment modality that may be thousands of years old and involves the application of live bee stings to the patient's skin or, in more recent years, the injection of bee venom into the skin with a hypodermic needle. Studies have proven the effectiveness of bee venom in treating pathological conditions such as arthritis, pain and cancerous tumors. However, there has not been sufficient review to fully elucidate the cellular mechanisms of the anti-inflammatory effects of bee venom and its components. In this respect, the present study reviews current understanding of the mechanisms of the anti-inflammatory properties of bee venom and its components in the treatment of liver fibrosis, atherosclerosis and skin disease.
摘要
蜂毒疗法是一种可能已有数千年历史的治疗方式，包括将活蜂蛰刺应用于患者皮肤，或者近年来采用皮下注射针将蜂毒注入皮肤。研究已证实蜂毒在治疗诸如关节炎、疼痛和癌性肿瘤等病理状况方面的有效性。然而，尚未有充分的综述来全面阐明蜂毒及其成分抗炎作用的细胞机制。在这方面，本研究综述了目前对蜂毒及其成分在治疗肝纤维化、动脉粥样硬化和皮肤病中的抗炎特性机制的理解。
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