自由基促进的α,β-不饱和酸与硅烷的立体特异性脱羧硅烷化反应。
A Free-Radical-Promoted Stereospecific Decarboxylative Silylation of α,β-Unsaturated Acids with Silanes.
机构信息
State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Tianshui South Road, No. 222, Lanzhou, Gansu 730000 (P.R. China).
出版信息
Angew Chem Int Ed Engl. 2016 Jan 4;55(1):236-9. doi: 10.1002/anie.201509537. Epub 2015 Nov 19.
A stereospecific decarboxylative silylation of acrylic and propiolic acids with silanes was developed. This reaction represents the first example of decarboxylative C-Si bond formation and provides an efficient and convenient approach to various synthetically useful alkenyl and alkynyl organosilicon compounds through the reaction of α,β-unsaturated acids with silanes. Spin-trapping and EPR experiments support a radical addition/elimination process.
发展了一种与硅烷的丙烯酸和丙炔酸的立体特异性脱羧硅烷化反应。该反应代表了首例脱羧 C-Si 键形成的反应，通过α,β-不饱和酸与硅烷的反应，为各种合成有用的烯基和炔基有机硅化合物提供了一种有效且方便的方法。自旋捕获和 EPR 实验支持自由基加成/消除过程。
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