Bein T, Klapproth C E
Institut für Anästhesiologie, Ludwig-Maximilians-Universität, München.
Anasth Intensivther Notfallmed. 1989 Apr;24(2):77-80.
The technique of in vitro fertilization (IVF) was simplified by the development of ultrasound-supported transvaginal follicular centesis. This makes it possible to dispense with general anesthesia. As an alternative, an intravenous analgosedation with midazolam (0.1 mg/kg) and fentanyl (2 micrograms/kg) is presented. Besides a good analgesic and anxiolytic action, an incipient respiratory depression was observed, so that insufflation of oxygen-enriched air is to be recommended. The operation is felt to be comfortable by almost all patients. A high degree of anterograde amnesia is attained. Meticulous intraoperative and postoperative anesthesiological monitoring is a prerequisite for application of this procedure.
超声辅助经阴道卵泡穿刺术的发展简化了体外受精（IVF）技术。这使得无需全身麻醉成为可能。作为替代方案，提出了使用咪达唑仑（0.1毫克/千克）和芬太尼（2微克/千克）进行静脉镇痛镇静。除了良好的镇痛和抗焦虑作用外，还观察到初期呼吸抑制，因此建议吹入富氧空气。几乎所有患者都感觉手术很舒适。可实现高度的顺行性遗忘。细致的术中和术后麻醉监测是应用该程序的前提条件。
