Kinetic modeling and the rise of systems pharmacology.
作者信息
Phair Robert D
机构信息
Integrative Bioinformatics Inc., Mountain View, CA 94041
出版信息
J Lipid Res. 2016 Jan;57(1):1-3. doi: 10.1194/jlr.C065482. Epub 2015 Nov 20.
Abstract
摘要
相似文献
1
Kinetic modeling and the rise of systems pharmacology.
J Lipid Res. 2016 Jan;57(1):1-3. doi: 10.1194/jlr.C065482. Epub 2015 Nov 20.
2
Where Do PBPK Models Stand in Pharmacometrics and Systems Pharmacology?
CPT Pharmacometrics Syst Pharmacol. 2020 Feb;9(2):75-76. doi: 10.1002/psp4.12493. Epub 2020 Jan 26.
3
Systems pharmacology for drug discovery and development: paradigm shift or flash in the pan?
Clin Pharmacol Ther. 2013 May;93(5):379-81. doi: 10.1038/clpt.2013.40.
4
Integration not isolation: arguing the case for quantitative and systems pharmacology in drug discovery and development.
Drug Discov Today. 2011 Dec;16(23-24):1031-6. doi: 10.1016/j.drudis.2011.10.001. Epub 2011 Oct 13.
5
Experiencing organ systems pharmacology first hand: thinking beyond the cell.
Mol Interv. 2010 Oct;10(5):259-62. doi: 10.1124/mi.10.5.2.
6
Potential Issues With Virtual Populations When Applied to Nonlinear Quantitative Systems Pharmacology Models.
CPT Pharmacometrics Syst Pharmacol. 2020 Nov;9(11):613-616. doi: 10.1002/psp4.12559. Epub 2020 Sep 24.
7
Application of pharmacometrics and quantitative systems pharmacology to cancer therapy: The example of luminal a breast cancer.
Pharmacol Res. 2017 Oct;124:20-33. doi: 10.1016/j.phrs.2017.07.015. Epub 2017 Jul 19.
8
Quantitative systems pharmacology as an extension of PK/PD modeling in CNS research and development.
J Pharmacokinet Pharmacodyn. 2013 Jun;40(3):257-65. doi: 10.1007/s10928-013-9297-1. Epub 2013 Jan 22.
9
Systems approaches for identifying disease genes and drug targets.
Methods. 2017 Dec 1;131:1-3. doi: 10.1016/j.ymeth.2017.10.002. Epub 2017 Oct 9.
10
Bridging pharmacology and pathophysiology via systems modeling.
J Clin Pharmacol. 2010 Sep;50(9 Suppl):56S-57S. doi: 10.1177/0091270010377505.
本文引用的文献
1
The Systems Biology Markup Language (SBML): Language Specification for Level 3 Version 1 Core.
J Integr Bioinform. 2015 Sep 4;12(2):266. doi: 10.2390/biecoll-jib-2015-266.
2
An in-silico model of lipoprotein metabolism and kinetics for the evaluation of targets and biomarkers in the reverse cholesterol transport pathway.
PLoS Comput Biol. 2014 Mar 13;10(3):e1003509. doi: 10.1371/journal.pcbi.1003509. eCollection 2014 Mar.
3
BioModels Database: a free, centralized database of curated, published, quantitative kinetic models of biochemical and cellular systems.
Nucleic Acids Res. 2006 Jan 1;34(Database issue):D689-91. doi: 10.1093/nar/gkj092.
4
Lipoprotein cholesteryl ester production, transfer, and output in vivo in humans.
J Lipid Res. 2004 Sep;45(9):1594-607. doi: 10.1194/jlr.M300511-JLR200. Epub 2004 May 16.
5
The formulation and testing of models.
Ann N Y Acad Sci. 1963 May 10;108:182-94. doi: 10.1111/j.1749-6632.1963.tb13373.x.
6
Computational systems biology.
Nature. 2002 Nov 14;420(6912):206-10. doi: 10.1038/nature01254.
7
Systems biology: a brief overview.
Science. 2002 Mar 1;295(5560):1662-4. doi: 10.1126/science.1069492.
8
Evaluation of apoA-I kinetics in humans using simultaneous endogenous stable isotope and exogenous radiotracer methods.
J Lipid Res. 1993 Dec;34(12):2207-15.
9
Circulation: overall regulation.
Annu Rev Physiol. 1972;34:13-46. doi: 10.1146/annurev.ph.34.030172.000305.
10
Computer simulation of metabolism in pyruvate-perfused rat heart. V. Physiological implications.
Am J Physiol. 1979 Sep;237(3):R181-6. doi: 10.1152/ajpregu.1979.237.3.R181.
Zotero 插件