Kitano Hiroaki
Sony Computer Science Laboratories, Inc., 3-14-13 Higashi-Gotanda, Shinagawa, Tokyo 141-0022, Japan.
Science. 2002 Mar 1;295(5560):1662-4. doi: 10.1126/science.1069492.
To understand biology at the system level, we must examine the structure and dynamics of cellular and organismal function, rather than the characteristics of isolated parts of a cell or organism. Properties of systems, such as robustness, emerge as central issues, and understanding these properties may have an impact on the future of medicine. However, many breakthroughs in experimental devices, advanced software, and analytical methods are required before the achievements of systems biology can live up to their much-touted potential.
要在系统层面理解生物学，我们必须研究细胞和机体功能的结构与动态，而非细胞或机体孤立部分的特征。系统特性，如稳健性，成为核心问题，理解这些特性可能会对医学的未来产生影响。然而，在系统生物学的成果能够实现其备受吹捧的潜力之前，还需要在实验设备、先进软件和分析方法方面取得许多突破。
