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江苏省无锡市340名婴儿急性呼吸道感染情况分析

Characterization of acute respiratory infections among 340 infants in Wuxi, Jiangsu Province.

作者信息

Ge Xiaoli, Han Zhijun, Chen Hongmin, Cheng Juanjuan, Gao Mingzhu, Sun Haibin

机构信息

1 Department of Pediatrics, 2 Department of Laboratory Medicine, Wuxi Second People's Hospital of Nanjing Medical University, Wuxi 214002, China ; 3 Department of Pediatrics, Wuxi People's Hospital of Nanjing Medical University, Wuxi 214002, China.

出版信息

Ann Transl Med. 2015 Oct;3(18):264. doi: 10.3978/j.issn.2305-5839.2015.10.23.

Abstract

BACKGROUND

To investigate the etiological and epidemiological features of acute respiratory infections among children in Wuxi, Jiangsu Province.

METHODS

Nasopharyngeal swab specimens were collected from 340 pediatric patients from Wuxi Second People's Hospital from June 2012 to May 2014. Seven respiratory viruses including influenza virus A (FA), influenza virus B (FB), parainfluenza virus I (PIVI), parainfluenza virus II (PIVII), parainfluenza virus III (PIVIII), adenovirus (ADV), and respiratory syncytial virus (RSV) were detected using direct immunofluorescence method. Epidemiological analysis was performed in terms of gender, age, and seasonal distribution.

RESULTS

Among these 340 patients, viral pathogens were detected in 116 cases (34.12%), with the leading three viruses being RSV (16.18%; 55/340), FB (5.29%; 18/340), and FA (5.00%; 17/340). The positive rate was not significantly different between male (36.32%; 73/201) and female (31.65%; 44/139) patients (P>0.05). The positive rate was highest in the 0-1-year-old group (48.48%; 32/66) and in winter (42.72%; 44/103).

CONCLUSIONS

RSV is the most commonly detected respiratory virus in Wuxi. Infants aged 0-1 year should be a priority population during disease prevention and control. Respiratory infections among children are more common in winter.

摘要

背景

调查江苏省无锡市儿童急性呼吸道感染的病因及流行病学特征。

方法

收集2012年6月至2014年5月无锡市第二人民医院340例儿科患者的鼻咽拭子标本。采用直接免疫荧光法检测甲型流感病毒(FA)、乙型流感病毒(FB)、副流感病毒I(PIVI)、副流感病毒II(PIVII)、副流感病毒III(PIVIII)、腺病毒(ADV)和呼吸道合胞病毒(RSV)7种呼吸道病毒。从性别、年龄和季节分布方面进行流行病学分析。

结果

在这340例患者中,116例(34.12%)检测到病毒病原体,前三位病毒为RSV(16.18%;55/340)、FB(5.29%;18/340)和FA(5.00%;17/340)。男性患者(36.32%;73/201)和女性患者(31.65%;44/139)的阳性率差异无统计学意义(P>0.05)。0-1岁组阳性率最高(48.48%;32/66),冬季阳性率最高(42.72%;44/103)。

结论

RSV是无锡最常检测到的呼吸道病毒。0-1岁婴儿应作为疾病防控的重点人群。儿童呼吸道感染在冬季更为常见。

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Characterization of acute respiratory infections among 340 infants in Wuxi, Jiangsu Province.
Ann Transl Med. 2015 Oct;3(18):264. doi: 10.3978/j.issn.2305-5839.2015.10.23.

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