Knezevic Nebojsa Nick, Candido Kenneth D, Desai Ravi, Kaye Alan David
Department of Anesthesiology, Advocate Illinois Masonic Medical Center, 836 West Wellington Avenue, Suite 4815, Chicago, IL 60657, USA; Department of Anesthesiology, University of Illinois, 1740 W. Taylor St, Chicago, IL 60612, USA.
Department of Anesthesiology, Advocate Illinois Masonic Medical Center, 836 West Wellington Avenue, Suite 4815, Chicago, IL 60657, USA.
Med Clin North Am. 2016 Jan;100(1):199-217. doi: 10.1016/j.mcna.2015.08.014.
Platelet-rich plasma (PRP) has the potential to regenerate tissues and decrease pain through the effects of bioactive molecules and growth factors present in alpha granules. Several PRP preparation systems are available with varying end products, doses of growth factors, and bioactive molecules. This article presents the biology of PRP, the preparation of PRP, and the effects PRP-related growth factors have on tissue healing and repair. Based on available evidence-based literature, the success of PRP therapy depends on the method of preparation and composition of PRP, the patient's medical condition, anatomic location of the injection, and the type of tissue injected.
富含血小板血浆（PRP）有潜力通过α颗粒中存在的生物活性分子和生长因子的作用来促进组织再生并减轻疼痛。有几种PRP制备系统可供使用，其最终产品、生长因子剂量和生物活性分子各不相同。本文介绍了PRP的生物学特性、PRP的制备以及PRP相关生长因子对组织愈合和修复的影响。基于现有循证文献，PRP治疗的成功取决于PRP的制备方法和成分、患者的病情、注射的解剖位置以及注射的组织类型。
