脑室内注射胰岛素可减弱大鼠被动回避反应的恢复。
Intracerebroventricular administration of insulin attenuates retrieval of a passive avoidance response in rats.
作者信息
Schwarzberg H, Bernstein H G, Reiser M, Günther O
机构信息
Institute of Physiology, Medical Academy Magdeburg, German Democratic Republic.
出版信息
Neuropeptides. 1989 Feb-Mar;13(2):79-81. doi: 10.1016/0143-4179(89)90002-4.
PMID:2662052
Abstract
The effect of intracerebroventricularly applied insulin on one-trial learning passive avoidance behaviour has been studied in rats. Treatment with 10.3 pmole insulin 1 hr before the 24 hr retention test attenuated passive avoidance behaviour at both the 24 hr and 48 hr retention trials. The data suggest that insulin may play a role in processes relating to the retrieval of information stored in the brain.
摘要
已在大鼠中研究了脑室内注射胰岛素对一次性学习被动回避行为的影响。在24小时记忆测试前1小时用10.3皮摩尔胰岛素进行处理，在24小时和48小时记忆试验中均减弱了被动回避行为。数据表明，胰岛素可能在与大脑中存储信息的检索相关的过程中发挥作用。
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