Department of Public Health Sciences, Division of Epidemiology, University of Rochester School of Medicine and Dentistry, 265 Crittenden Blvd., CU 420644, Rochester, NY, 14642-0644, USA.
Department of Public Health Sciences, Division of Social and Behavioral Sciences, University of Rochester School of Medicine and Dentistry, 265 Crittenden Blvd., CU 420644, Rochester, NY, 14642-0644, USA.
Curr Obes Rep. 2014 Jun;3(2):223-34. doi: 10.1007/s13679-014-0100-4.
Worksites provide multiple advantages to prevent and treat obesity and to test environmental interventions to tackle its multiple causal factors. We present a literature review of group-randomized and non-randomized trials that tested worksite environmental, multiple component interventions for obesity prevention and control paying particular attention to the conduct of formative research prior to intervention development. The evidence on environmental interventions on measures of obesity appears to be strong since most of the studies have a low (4/8) and unclear (2/8) risk of bias. Among the studies reviewed whose potential risk of bias was low, the magnitude of the effect was modest and sometimes in the unexpected direction. None of the four studies describing an explicit formative research stage with clear integration of findings into the intervention was able to demonstrate an effect on the main outcome of interest. We present alternative explanation for the findings and recommendations for future research.
工作场所为预防和治疗肥胖症以及测试解决其多种因果因素的环境干预措施提供了多种优势。我们对测试工作场所环境、多组分干预肥胖预防和控制的群组随机和非随机试验进行了文献回顾，特别关注干预措施制定前的形成性研究的开展情况。关于环境干预措施对肥胖衡量指标的证据似乎很有力，因为大多数研究的偏倚风险较低（8 项研究中 4 项/8 项）和不明确（8 项研究中 2 项/8 项）。在回顾的研究中，潜在偏倚风险较低的研究中，干预效果的幅度适中，有时与预期方向相反。没有一项描述明确的形成性研究阶段并将研究结果明确纳入干预措施的研究能够证明对主要研究结果有影响。我们提出了对这些发现的替代解释，并为未来的研究提出了建议。
