Brennan Penny L, SooHoo Sonya, Lemke Sonne, Schutte Kathleen K
VA Palo Alto Health Care System, Menlo Park, CA, USA
VA Palo Alto Health Care System, Menlo Park, CA, USA.
J Aging Health. 2016 Aug;28(5):911-32. doi: 10.1177/0898264315615837. Epub 2015 Dec 1.
To determine effects of late-middle-aged adults' baseline drinking behavior on their subsequent 10-year depressive symptom trajectories.
Health and Retirement Study participants (N = 7,939) were assessed on baseline demographic, health, and drinking characteristics, and biennially assessed for the next 10 years on their depressive symptoms.
Growth mixture modeling generated four classes of depressive symptom trajectories: Consistently low (72%), consistently elevated (6%), increasing (12%), and decreasing (10%). Baseline abstinence from alcohol, possibly enforced by poorer health and a history of drinking problems, and heavier drinking, "binge" drinking, and having a history of drinking problems, raised risk of membership in the "consistently elevated" class. Abstinence by participants without history of drinking problems-and light, moderate, and heavier drinking-protected against membership in the "increasing" class. Abstinence by participants without history of drinking problems elevated-and moderate drinking reduced-likelihood of membership in the "decreasing" class.
Late-middle-aged adults' alcohol use is associated with the subsequent long-term course of their depressive symptoms.
确定中老年成年人的基线饮酒行为对其随后10年抑郁症状轨迹的影响。
对健康与退休研究的参与者（N = 7939）进行基线人口统计学、健康状况和饮酒特征评估，并在接下来的10年中每两年对其抑郁症状进行评估。
生长混合模型产生了四类抑郁症状轨迹：持续低水平（72%）、持续高水平（6%）、上升（12%）和下降（10%）。基线戒酒，可能是由于健康状况较差和有饮酒问题史所致，以及大量饮酒、“暴饮”和有饮酒问题史，会增加属于“持续高水平”类别的风险。无饮酒问题史的参与者戒酒以及少量、适量和大量饮酒可预防属于“上升”类别的情况。无饮酒问题史的参与者戒酒会增加属于“下降”类别的可能性，而适量饮酒则会降低这种可能性。
中老年成年人的饮酒与他们随后抑郁症状的长期病程有关。
