中国男性类风湿关节炎与骨质疏松症的关联：一项基于社区的研究
Association between rheumatoid arthritics and osteoporosis among Chinese men, a community based study.
作者信息
Piao Hui-Hong, Zhang Ke-Qin, Tang Zi-Hui
机构信息
Department of Edocrinology and Metabolism, Shanghai Tongji Hospital, Tongji University School of Medicine Shanghai, China.
出版信息
Int J Clin Exp Med. 2015 Sep 15;8(9):16592-8. eCollection 2015.
BACKGROUND
The main purpose of this study was to estimate the associations between rheumatoid arthritics (RA) and osteoporosis (OP) in general Chinese men.
METHODS
We conducted a large-scale, community-based, cross-sectional study to investigate the associations by using self-report questionnaire to access medical history. A total of 1041 men were recruited sis in this study. Multiple regression models controlling for confounding factors to include RA were performed to investigate the relationships for OP.
RESULTS
Univariate analysis indicated there was no significant association between RA and T-score (P = 0.103), however, significant association between RA and OP was reported (P = 0.005). Multiple regression analysis indicated that RA was significantly associated with OP (P = 0.013, OR = 3.191 95% CI: 1.284-7.932). The men with RA had a significant higher prevalence of OP.
CONCLUSION
The findings indicated that RA was independently and significantly associated with OP. The prevalence of OP was less frequent in Chinese men without RA.
背景
本研究的主要目的是评估中国普通男性类风湿关节炎（RA）与骨质疏松症（OP）之间的关联。
方法
我们开展了一项大规模、基于社区的横断面研究，通过使用自我报告问卷获取病史来调查这种关联。本研究共招募了1041名男性。采用多元回归模型控制包括RA在内的混杂因素，以研究与OP的关系。
结果
单因素分析表明，RA与T值之间无显著关联（P = 0.103），然而，报告显示RA与OP之间存在显著关联（P = 0.005）。多元回归分析表明，RA与OP显著相关（P = 0.013，OR = 3.191，95%CI：1.284 - 7.932）。患有RA的男性OP患病率显著更高。
结论
研究结果表明，RA与OP独立且显著相关。无RA的中国男性中OP患病率较低。
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