Li Xia, Lei Tao, Tang Zihui, Dong Jingcheng
Department of Endocrinology and Metabolism, Shanghai Tongji Hospital, Tongji University School of Medicine, Shanghai, China.
Department of Integrative Medicine, Huashan Hospital, Fudan University, No.12 Urumqi Middle Road, 200040, Shanghai, China.
J Health Popul Nutr. 2017 Apr 19;36(1):13. doi: 10.1186/s41043-017-0088-y.
The main purpose of this study was to estimate the associations between frequency of fish food consumption and osteoporosis (OP) in general Chinese men.
We conducted a large-scale, community-based, cross-sectional study to investigate the associations by using self-report questionnaire to access frequency of fish food intake. A total of 1092 men were available for data analysis in this study. Multiple regression models controlling for confounding factors to include frequency of fish food consumption variable were performed to investigate the relationships for OP.
Positive correlations between frequency of fish food consumption and T score were reported (β = 0.084, P value = 0.025). Multiple regression analysis indicated that the frequency of fish food consumption was significantly associated with OP (P < 0.05 for model 1 and model 2). The men with high frequency of fish food consumption had a lower prevalence of OP.
The findings indicated that frequency of fish food consumption was independently and significantly associated with OP. The prevalence of OP was less frequent in Chinese men preferring fish food habits.
ClinicalTrials.gov Identifier: NCT02451397 retrospectively registered 28 May 2015.
本研究的主要目的是评估中国成年男性鱼类食物消费频率与骨质疏松症（OP）之间的关联。
我们开展了一项大规模的、基于社区的横断面研究，通过自填式问卷调查鱼类食物摄入频率来调查两者之间的关联。本研究共有1092名男性纳入数据分析。采用多元回归模型，控制包括鱼类食物消费频率变量在内的混杂因素，以研究与OP的关系。
报告显示鱼类食物消费频率与T值呈正相关（β = 0.084，P值 = 0.025）。多元回归分析表明，鱼类食物消费频率与OP显著相关（模型1和模型2的P < 0.05）。鱼类食物消费频率高的男性OP患病率较低。
研究结果表明，鱼类食物消费频率与OP独立且显著相关。有食用鱼类饮食习惯的中国男性OP患病率较低。
ClinicalTrials.gov标识符：NCT02451397，于2015年5月28日进行回顾性注册。
