中国男性咖啡摄入量频率的主观评估及其与骨质疏松症的关系
Subjective evaluation of the frequency of coffee intake and relationship to osteoporosis in Chinese men.
作者信息
Yu Qian, Liu Zhong-Hua, Lei Tao, Tang Zihui
机构信息
Department of Endocrinology and Metabolism, Shanghai Tongji Hospital, Tongji University School of Medicine, Shanghai, 200065, China.
Shanghai Changfeng Community Health Care Center, Putuo, Shanghai, China.
出版信息
J Health Popul Nutr. 2016 Aug 5;35(1):24. doi: 10.1186/s41043-016-0060-2.
BACKGROUND
The main purpose of this study was to evaluate the associations between frequency of coffee intake and osteoporosis (OP) in a general Chinese male sample.
METHODS
We conducted a large-scale, community-based, cross-sectional study to investigate the associations by using a self-report questionnaire to estimate the frequency of coffee intake. A total of 992 men were available for data analysis in this study. Multiple regression models controlling for confounding factors to include frequency of coffee intake variable were performed to investigate the relationships for OP.
RESULTS
Positive correlations between frequency of coffee intake and T-score were reported (β = 0.211, P = 0.024). Multiple regression analysis indicated that the frequency of coffee intake was significantly associated with OP (P < 0.05 for model 1 and model 2). The men with moderate frequency of coffee intake had a lower prevalence of OP.
CONCLUSIONS
The findings indicated that consumption of coffee was independently and significantly associated with OP. The prevalence of OP was less frequent in Chinese men with moderate coffee intake.
TRIAL REGISTRATION
ClinicalTrials.gov, NCT02451397.
背景
本研究的主要目的是评估中国普通男性样本中咖啡摄入频率与骨质疏松症（OP）之间的关联。
方法
我们开展了一项大规模、基于社区的横断面研究，通过使用自我报告问卷来估计咖啡摄入频率，以调查两者之间的关联。本研究共有992名男性可用于数据分析。进行了控制混杂因素（包括咖啡摄入频率变量）的多元回归模型，以研究与骨质疏松症的关系。
结果
报告显示咖啡摄入频率与T值呈正相关（β = 0.211，P = 0.024）。多元回归分析表明，咖啡摄入频率与骨质疏松症显著相关（模型1和模型2的P < 0.05）。咖啡摄入频率适中的男性骨质疏松症患病率较低。
结论
研究结果表明，咖啡消费与骨质疏松症独立且显著相关。咖啡摄入频率适中的中国男性骨质疏松症患病率较低。
试验注册
ClinicalTrials.gov，NCT02451397。
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